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CAS 202475-60-3 JAK3 INHIBITOR I molecular structure lightbox
CAS RN: 202475-60-3

JAK3 INHIBITOR I

Product Availability

Choose a grade to view its available package options.

8 package records7 with current stock1 grade group
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20251113 100mg In stock Shenzhen, Tianjin Inquiry
Batchno.20260208 10mg In stock Shanghai, Wuhan Inquiry
Batchno.20250209 1g Out of stock Inquiry
Batchno.20260606 1mg In stock Shanghai, Wuhan Inquiry
Batchno.20251018 250mg In stock Tianjin Inquiry
Batchno.20251117 25mg In stock Shanghai, Wuhan Inquiry
Batchno.20250618 50mg In stock Shanghai Inquiry
Batchno.20260612 5mg In stock Shanghai, Wuhan Inquiry
  • Product code: SSC-095365
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Historical Factory Record

Historical Supply Reference

This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.

  • Pack sizes on record: 0.25g
  • Available purity: ≥95%
  • Inventory rows with stock: 0
  • Bulk packaging: confirmed by inquiry
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Reference Pack Sizes

Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 202475-60-3
Pack Size Recorded Purity Available Qty Ship From Inquiry
0.25g ≥95% 0 Out of Stock Beijing Inquiry

202475-60-3 / 4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol

Standard CAS: 202475-60-3 Multi CAS: No
Basic Information Computed Properties

Basic Information

CAS
202475-60-3
Multi CAS
No
Molecular Formula
C16H15N3O3
Molecular Weight
297.310000
Exact Mass
297.111341
SMILES
COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)O)OC
InChI
InChI=1S/C16H15N3O3/c1-21-14-7-12-13(8-15(14)22-2)17-9-18-16(12)19-10-3-5-11(20)6-4-10/h3-9,20H,1-2H3,(H,17,18,19)
InChIKey
HOZUXBLMYUPGPZ-UHFFFAOYSA-N

Computed Properties

Structural Parameters

Heavy atom count
22
Aromatic heavy atom count
16
Fraction Csp3
0.12
Rotatable bonds
4
H-bond acceptors
6
H-bond donors
2
Molar refractivity
84.03
TPSA
76.5

LogP / Solubility

WLOGP
3.1
MLOGP
2.74
XLogP3
3
Consensus LogP
2.95
Log S (ESOL)
-3.91
Class (ESOL)
Poorly soluble
Log S (Ali)
-4.23
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-4.64
Class (SILICOS-IT)
Slightly soluble

ADME

GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-2.34

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
Yes
Synthetic Accessibility
2.5

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