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CAS 193275-84-2 LONAFARNIB molecular structure lightbox
CAS RN: 193275-84-2

LONAFARNIB

Product Availability

Choose a grade to view its available package options.

9 package records8 with current stock2 grade groups
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20250204 100mg In stock Shanghai Inquiry
Batchno.20250122 10mg In stock Shanghai Inquiry
Batchno.20260610 1g Out of stock Inquiry
Batchno.20250803 1mg In stock Shanghai Inquiry
Batchno.20250514 250mg In stock Shanghai, Shenzhen Inquiry
Batchno.20250403 25mg In stock Shanghai Inquiry
Batchno.20250803 50mg In stock Shanghai Inquiry
Batchno.20260130 5mg In stock Shanghai Inquiry
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20251209 1mg / 5mg / 25mg / 100mg Confirm by inquiry Shanghai, Shandong, Chongqing Inquiry
  • Product code: SSC-090680
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Historical Factory Record

Historical Supply Reference

This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.

  • Pack sizes on record: 0.25g
  • Available purity: ≥95%
  • Inventory rows with stock: 0
  • Bulk packaging: confirmed by inquiry
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Reference Pack Sizes

Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 193275-84-2
Pack Size Recorded Purity Available Qty Ship From Inquiry
0.25g ≥95% 0 Out of Stock Shanghai Inquiry

193275-84-2 / 4-[2-[4-[(2R)-6,15-dibromo-13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl]piperidin-1-yl]-2-oxoethyl]piperidine-1-carboxamide

Standard CAS: 193275-84-2 Multi CAS: No
Basic Information Computed Properties Safety & Transport

Basic Information

CAS
193275-84-2
Multi CAS
No
Molecular Formula
C27H31Br2ClN4O2
Molecular Weight
638.800000
Exact Mass
638.048180
SMILES
C1CN(CCC1CC(=O)N2CCC(CC2)[C@@H]3C4=C(CCC5=C3N=CC(=C5)Br)C=C(C=C4Br)Cl)C(=O)N
InChI
InChI=1S/C27H31Br2ClN4O2/c28-20-12-19-2-1-18-13-21(30)14-22(29)24(18)25(26(19)32-15-20)17-5-9-33(10-6-17)23(35)11-16-3-7-34(8-4-16)27(31)36/h12-17,25H,1-11H2,(H2,31,36)/t25-/m1/s1
InChIKey
DHMTURDWPRKSOA-RUZDIDTESA-N

Computed Properties

Structural Parameters

Heavy atom count
36
Aromatic heavy atom count
12
Fraction Csp3
0.52
Rotatable bonds
3
H-bond acceptors
3
H-bond donors
1
Molar refractivity
148.14
TPSA
79.53

LogP / Solubility

WLOGP
5.91
MLOGP
5.25
XLogP3
4.8
Consensus LogP
5.32
Log S (ESOL)
-7.57
Class (ESOL)
Insoluble
Log S (Ali)
-9.07
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-9.08
Class (SILICOS-IT)
Insoluble

ADME

GI absorption
Low
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-2.42

Drug-likeness / Medicinal Chemistry

Lipinski
No
Ghose
No
Veber
Yes
Egan
No
Muegge
No
Bioavailability score
0.17
Leadlikeness
No
Synthetic Accessibility
5.5

Safety & Transport

Pictogram(s)
Health Hazard
Signal
Warning
GHS Hazard Statements
H361 (91.7%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity] H373 (91.7%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]
Precautionary Statement Codes
P203, P260, P280, P318, P319, P405, and P501

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