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CAS 190791-29-8 Lasofoxifene Tartrate molecular structure lightbox
CAS RN: 190791-29-8

Lasofoxifene Tartrate

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3 package records2 with current stock1 grade group
Batch No.PackageAvailabilityInquiry
Batchno.20260312 100mg Out of stock Inquiry
Batchno.20250216 10mg In stock Inquiry
Batchno.20251103 50mg In stock Inquiry
  • Product code: ICTL0336
  • Purity/Analytical Methods: >98.0%(HPLC)
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190791-29-8 / (2S,3S)-2,3-dihydroxybutanedioic acid;(5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol

Standard CAS: 190791-29-8 Multi CAS: No
Basic Information Computed Properties Safety & Transport

Basic Information

CAS
190791-29-8
Multi CAS
No
Molecular Formula
C32H37NO8
Molecular Weight
563.600000
Exact Mass
563.251917
SMILES
C1CCN(C1)CCOC2=CC=C(C=C2)[C@H]3[C@H](CCC4=C3C=CC(=C4)O)C5=CC=CC=C5.[C@H]([C@@H](C(=O)O)O)(C(=O)O)O
InChI
InChI=1S/C28H31NO2.C4H6O6/c30-24-11-15-27-23(20-24)10-14-26(21-6-2-1-3-7-21)28(27)22-8-12-25(13-9-22)31-19-18-29-16-4-5-17-29;5-1(3(7)8)2(6)4(9)10/h1-3,6-9,11-13,15,20,26,28,30H,4-5,10,14,16-19H2;1-2,5-6H,(H,7,8)(H,9,10)/t26-,28+;1-,2-/m10/s1
InChIKey
INEHJXCWEVNEDZ-LUDNRVPPSA-N

Computed Properties

Structural Parameters

Heavy atom count
41
Aromatic heavy atom count
18
Fraction Csp3
0.38
Rotatable bonds
9
H-bond acceptors
7
H-bond donors
5
Molar refractivity
152.35
TPSA
147.76

LogP / Solubility

WLOGP
3.61
MLOGP
3.22
XLogP3
3.61
Consensus LogP
3.48
Log S (ESOL)
-5.34
Class (ESOL)
Slightly soluble
Log S (Ali)
-6.79
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-7.4
Class (SILICOS-IT)
Insoluble

ADME

GI absorption
Low
BBB permeant
No
P-gp substrate
Yes
CYP1A2 inhibitor
No
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-3.6

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
No
Egan
No
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
7

Safety & Transport

Pictogram(s)
Corrosive Health Hazard Environmental Hazard
Signal
Danger
GHS Hazard Statements
H318 (100%): Causes serious eye damage [Danger Serious eye damage/eye irritation] H360 (100%): May damage fertility or the unborn child [Danger Reproductive toxicity] H372 (100%): Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] H410 (100%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]
Precautionary Statement Codes
P203, P260, P264, P264+P265, P270, P273, P280, P305+P354+P338, P317, P318, P319, P391, P405, and P501

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