This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.
Streptozocin is an off-white powder. Melting point 115 °C. Used as an anti-cancer drug. Carcinogenic.
Ivory-colored or pale yellow solid; [HSDB] Light yellow crystalline solid;
Solid
Appearance
POINTED PLATELETS OR PRISMS FROM 95% ETHANOL
PALE-YELLOW CRYSTALS
Ivory-colored crystalline powder
State
Solid
Storage Conditions
PRECAUTIONS FOR "CARCINOGENS": Storage site should be as close as practical to lab in which carcinogens are to be used, so that only small quantities required for ... expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion-proof refrigerator or freezer (depending on chemicophysical properties ...) that bears appropriate label. An inventory ... should be kept, showing quantity of carcinogen & date it was acquired ... Facilities for dispensing ... should be contiguous to storage area. /Chemical Carcinogens/
Computed Properties
Structural Parameters
Heavy atom count
18
Fraction Csp3
0.88
Rotatable bonds
3
H-bond acceptors
8
H-bond donors
5
Molar refractivity
55.86
TPSA
151.92
LogP / Solubility
WLOGP
-2.89
MLOGP
-2.54
XLogP3
-1.4
Consensus LogP
-2.28
Log S (ESOL)
0.53
Class (ESOL)
Highly soluble
Log S (Ali)
0.35
Class (Ali)
Highly soluble
Log S (SILICOS-IT)
0.66
Class (SILICOS-IT)
Highly soluble
ADME
GI absorption
Low
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-6.39
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
No
Veber
No
Egan
No
Muegge
No
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
Yes
Synthetic Accessibility
4
Safety & Transport
Pictogram(s)
Irritant
Health Hazard
Acute Toxic
Signal
Danger
GHS Hazard Statements
H312 (22.8%): Harmful in contact with skin [Warning Acute toxicity, dermal]
H332 (22.8%): Harmful if inhaled [Warning Acute toxicity, inhalation]
H340 (22.8%): May cause genetic defects [Danger Germ cell mutagenicity]
H350 (96.5%): May cause cancer [Danger Carcinogenicity]
H360 (22.8%): May damage fertility or the unborn child [Danger Reproductive toxicity]