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CAS 186497-07-4 Zibotentan (ZD4054) molecular structure lightbox
CAS RN: 186497-07-4

Zibotentan (ZD4054)

Product Availability

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8 package records7 with current stock1 grade group
Batch No.PackageAvailabilityWarehouseLead TimeInquiry
Batchno.20250115 100mg In stock Shanghai Inquiry
Batchno.20250708 10mg In stock Shanghai Inquiry
Batchno.20251007 10mg / 50mg / 250mg Out of stock 5-7 business days Inquiry
Batchno.20251117 1mg In stock Shanghai Inquiry
Batchno.20250220 250mg In stock Shanghai Inquiry
Batchno.20250522 25mg In stock Shanghai Inquiry
Batchno.20250426 50mg In stock Shanghai Inquiry
Batchno.20251229 5mg In stock Shanghai Inquiry
  • Product code: SSC-086609
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Historical Factory Record

Historical Supply Reference

This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.

  • Pack sizes on record: 0.1g
  • Available purity: ≥95%
  • Inventory rows with stock: 0
  • Bulk packaging: confirmed by inquiry
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Reference Pack Sizes

Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 186497-07-4
Pack Size Recorded Purity Available Qty Ship From Inquiry
0.1g ≥95% 0 Out of Stock Shanghai Inquiry

186497-07-4 / N-(3-methoxy-5-methylpyrazin-2-yl)-2-[4-(1,3,4-oxadiazol-2-yl)phenyl]pyridine-3-sulfonamide

Standard CAS: 186497-07-4 Multi CAS: No
Basic Information Computed Properties Safety & Transport

Basic Information

CAS
186497-07-4
Multi CAS
No
Molecular Formula
C19H16N6O4S
Molecular Weight
424.400000
Exact Mass
424.095374
SMILES
CC1=CN=C(C(=N1)OC)NS(=O)(=O)C2=C(N=CC=C2)C3=CC=C(C=C3)C4=NN=CO4
InChI
InChI=1S/C19H16N6O4S/c1-12-10-21-17(19(23-12)28-2)25-30(26,27)15-4-3-9-20-16(15)13-5-7-14(8-6-13)18-24-22-11-29-18/h3-11H,1-2H3,(H,21,25)
InChIKey
FJHHZXWJVIEFGJ-UHFFFAOYSA-N

Computed Properties

Structural Parameters

Heavy atom count
30
Aromatic heavy atom count
23
Fraction Csp3
0.11
Rotatable bonds
6
H-bond acceptors
9
H-bond donors
1
Molar refractivity
107.09
TPSA
132.99

LogP / Solubility

WLOGP
2.71
MLOGP
2.41
XLogP3
1.4
Consensus LogP
2.17
Log S (ESOL)
-4.35
Class (ESOL)
Slightly soluble
Log S (Ali)
-4.99
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-5.39
Class (SILICOS-IT)
Slightly soluble

ADME

GI absorption
Low
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-3.39

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
No
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
3

Safety & Transport

Pictogram(s)
Irritant Health Hazard Environmental Hazard
Signal
Danger
GHS Hazard Statements
H302 (25%): Harmful if swallowed [Warning Acute toxicity, oral] H360 (75%): May damage fertility or the unborn child [Danger Reproductive toxicity] H373 (75%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] H411 (75%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]
Precautionary Statement Codes
P203, P260, P264, P270, P273, P280, P301+P317, P318, P319, P330, P391, P405, and P501

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