![CAS 185133-82-8 IMidazo[1,2-a]pyridin-8-aMine, 2-(trifluoroMethyl)- molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/185133-82-8.gif)
CAS RN: 185133-82-8
IMidazo[1,2-a]pyridin-8-aMine, 2-(trifluoroMethyl)-
Product Availability
Choose a grade to view its available package options.
1 package records0 with current stock1 grade group
| Batch No. | Package | Availability | Lead Time | Inquiry |
|---|---|---|---|---|
| Batchno.20260304 | 50mg / 250mg | Out of stock | 8-10 business days | Inquiry |
- Product code: starshine_CAS185133-82-8
- Purity/Analytical Methods: >99.0%
185133-82-8 / 2-(trifluoromethyl)imidazo[1,2-a]pyridin-8-amine
Basic Information
CAS
185133-82-8
Multi CAS
No
Molecular Formula
C8H6F3N3
Molecular Weight
201.150000
Exact Mass
201.051382
SMILES
C1=CN2C=C(N=C2C(=C1)N)C(F)(F)F
InChI
InChI=1S/C8H6F3N3/c9-8(10,11)6-4-14-3-1-2-5(12)7(14)13-6/h1-4H,12H2
InChIKey
FLJWRLOENAETFF-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
14
Aromatic heavy atom count
9
Fraction Csp3
0.12
H-bond acceptors
3
H-bond donors
1
Molar refractivity
44.61
TPSA
43.32
LogP / Solubility
WLOGP
1.94
MLOGP
1.7
XLogP3
2
Consensus LogP
1.88
Log S (ESOL)
-2.78
Class (ESOL)
Moderately soluble
Log S (Ali)
-2.61
Class (Ali)
Moderately soluble
Log S (SILICOS-IT)
-2.57
Class (SILICOS-IT)
Moderately soluble
ADME
GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-2.57
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
1.5
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