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CAS 184475-35-2 Gefitinib molecular structure lightbox
CAS RN: 184475-35-2

Gefitinib

Product Availability

Choose a grade to view its available package options.

12 package records10 with current stock3 grade groups
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20250225 100g In stock Shandong Inquiry
Batchno.20260112 1g In stock Shanghai, Shandong, Hebei Inquiry
Batchno.20250418 25g In stock Shanghai, Shandong, Guangdong Inquiry
Batchno.20250816 5g In stock Shanghai, Shandong, Chongqing Inquiry
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20251117 100g Out of stock Inquiry
Batchno.20260526 10g In stock Inquiry
Batchno.20260406 1g In stock Inquiry
Batchno.20251014 250mg In stock Inquiry
Batchno.20260319 25g Out of stock Inquiry
Batchno.20260108 50mg In stock Inquiry
Batchno.20250520 5g In stock Inquiry
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20260607 1ml In stock Inquiry
  • Product code: SSC-085278
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Verified Factory Data

Supply Overview & Packaging Options

Packaging options, recorded purity, stock quantity and ship-from location below are generated from the current factory data table for this CAS.

  • Pack sizes on record: 1g, 5g, 10g, 25g, 100g, 1000g
  • Available purity: ≥98%
  • Inventory rows with stock: 2
  • Bulk packaging: confirmed by inquiry
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Available Pack Sizes & Stock

Specific stock quantities are shown below. Price is not displayed online and is confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 184475-35-2
Pack Size Recorded Purity Available Qty Ship From Inquiry
1g ≥98% 4 In Stock Beijing Inquiry
1g -- 3 In Stock Beijing Inquiry
5g -- 0 Out of Stock Beijing Inquiry
5g ≥98% 0 Out of Stock Shanghai Inquiry
10g -- 0 Out of Stock Beijing Inquiry
10g ≥98% 0 Out of Stock Hong Kong Inquiry
25g -- 0 Out of Stock Hong Kong Inquiry
25g ≥98% 0 Out of Stock Hong Kong Inquiry
100g -- 0 Out of Stock Beijing Inquiry
100g ≥98% 0 Out of Stock Shenzhen Inquiry
1000g -- 0 Out of Stock Hong Kong Inquiry

184475-35-2 / N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine

Standard CAS: 184475-35-2 Multi CAS: No
Basic Information Physical Properties Computed Properties Safety & Transport

Basic Information

CAS
184475-35-2
Multi CAS
No
Molecular Formula
C22H24ClFN4O3
Molecular Weight
446.900000
Exact Mass
446.152097
SMILES
COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4
InChI
InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)
InChIKey
XGALLCVXEZPNRQ-UHFFFAOYSA-N

Physical Properties

Physical Description
Solid
State
Solid

Computed Properties

Structural Parameters

Heavy atom count
31
Aromatic heavy atom count
16
Fraction Csp3
0.36
Rotatable bonds
8
H-bond acceptors
7
H-bond donors
1
Molar refractivity
118.15
TPSA
68.74

LogP / Solubility

WLOGP
4.28
MLOGP
3.79
XLogP3
4.1
Consensus LogP
4.06
Log S (ESOL)
-5.16
Class (ESOL)
Slightly soluble
Log S (Ali)
-6.31
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-7.07
Class (SILICOS-IT)
Insoluble

ADME

GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-2.41

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
3

Safety & Transport

Pictogram(s)
Corrosive Irritant Health Hazard Environmental Hazard
Signal
Danger
GHS Hazard Statements
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] H315 (73.8%): Causes skin irritation [Warning Skin corrosion/irritation] H318 (72.5%): Causes serious eye damage [Danger Serious eye damage/eye irritation] H351 (73.8%): Suspected of causing cancer [Warning Carcinogenicity] H361 (38.8%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]
Precautionary Statement Codes
P203, P260, P264, P264+P265, P270, P273, P280, P301+P317, P302+P352, P305+P354+P338, P317, P318, P319, P321, P330, P332+P317, P362+P364, P391, P405, and P501

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