CAS RN: 1823440-48-7
8-((triMethylsilyl)ethynyl)isoquinoline
Product Availability
Choose a grade to view its available package options.
1 package records0 with current stock1 grade group
| Batch No. | Package | Availability | Lead Time | Inquiry |
|---|---|---|---|---|
| Batchno.20250817 | 100mg | Out of stock | 8-10 business days | Inquiry |
- Product code: starshine_CAS1823440-48-7
- Purity/Analytical Methods: >99.0%
1823440-48-7 / 2-isoquinolin-8-ylethynyl(trimethyl)silane
Basic Information
CAS
1823440-48-7
Multi CAS
No
Molecular Formula
C14H15NSi
Molecular Weight
225.360000
Exact Mass
225.097376
SMILES
C[Si](C)(C)C#CC1=CC=CC2=C1C=NC=C2
InChI
InChI=1S/C14H15NSi/c1-16(2,3)10-8-13-6-4-5-12-7-9-15-11-14(12)13/h4-7,9,11H,1-3H3
InChIKey
FKAPASNVVPNCRO-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
16
Aromatic heavy atom count
10
Fraction Csp3
0.21
Rotatable bonds
2
H-bond acceptors
1
Molar refractivity
71.97
TPSA
12.89
LogP / Solubility
WLOGP
3.46
MLOGP
3.05
XLogP3
3.46
Consensus LogP
3.32
Log S (ESOL)
-3.88
Class (ESOL)
Poorly soluble
Log S (Ali)
-3.91
Class (Ali)
Poorly soluble
Log S (SILICOS-IT)
-4
Class (SILICOS-IT)
Poorly soluble
ADME
GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-1.64
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
1.5
Customers Also Viewed
-
![CAS 1823456-51-4 5-Bromo-8-methoxy-imidazo[1,2-a]pyridine molecular structure](data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%200%200'%3E%3C/svg%3E)
5-Bromo-8-methoxy-imidazo[1,2-a]pyridine
- CAS RN: 1823456-51-4
- Product Code: starshine_CAS1823456-51-4
- Purity/Analytical method: >99.0%
-
-
2-Methyl-3-(1,3,4-oxadiazol-2-yl)-6-(trifluoromethyl)pyridine
- CAS RN: 1823496-56-5
- Product Code: SSC-083746
-
3,9-Diaza-bicyclo[3.3.1]nonane-3-carboxylic acid tert-butyl ester
- CAS RN: 1823500-01-1
- Product Code: SSC-083751
-
BENZYL 8-AMINO-5-AZASPIRO[2.5]OCTANE-5-CARBOXYLATE HCL
- CAS RN: 1823500-42-0
- Product Code: starshine_CAS1823500-42-0
- Purity/Analytical method: >99.0%
-
6-((TERT-BUTOXYCARBONYL)AMINO)-2-OXASPIRO[3.3]HEPTANE-6-CARBOXYLIC ACID
- CAS RN: 1823515-64-5
- Product Code: starshine_CAS1823515-64-5
- Purity/Analytical method: >99.0%
![CAS 1823456-51-4 5-Bromo-8-methoxy-imidazo[1,2-a]pyridine molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1823456-51-4.gif)
![CAS 1823500-01-1 3,9-Diaza-bicyclo[3.3.1]nonane-3-carboxylic acid tert-butyl ester molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1823500-01-1.gif)
![CAS 1823500-42-0 BENZYL 8-AMINO-5-AZASPIRO[2.5]OCTANE-5-CARBOXYLATE HCL molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1823500-42-0.gif)
![CAS 1823515-64-5 6-((TERT-BUTOXYCARBONYL)AMINO)-2-OXASPIRO[3.3]HEPTANE-6-CARBOXYLIC ACID molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1823515-64-5.gif)