CAS RN: 1820787-94-7
IRAK4-IN-1
Product Availability
Choose a grade to view its available package options.
8 package records7 with current stock2 grade groups
| Batch No. | Package | Availability | Warehouse | Lead Time | Inquiry |
|---|---|---|---|---|---|
| Batchno.20250726 | 1mg / 5mg / 25mg | Out of stock | 5-7 business days | Inquiry |
| Batch No. | Package | Availability | Warehouse | Lead Time | Inquiry |
|---|---|---|---|---|---|
| Batchno.20250226 | 100mg | In stock | Shanghai | Inquiry | |
| Batchno.20250813 | 10mg | In stock | Shanghai | Inquiry | |
| Batchno.20260304 | 1mg | In stock | Shanghai | Inquiry | |
| Batchno.20260508 | 250mg | In stock | Shanghai | Inquiry | |
| Batchno.20251225 | 25mg | In stock | Shanghai | Inquiry | |
| Batchno.20250725 | 50mg | In stock | Shanghai | Inquiry | |
| Batchno.20250207 | 5mg | In stock | Shanghai | Inquiry |
- Product code: starshine_CAS1820787-94-7
- Purity/Analytical Methods: >99.0%
1820787-94-7 / 4-[(4-morpholin-4-ylcyclohexyl)amino]quinazoline-6-carbonitrile
Basic Information
CAS
1820787-94-7
Multi CAS
No
Molecular Formula
C19H23N5O
Molecular Weight
337.400000
Exact Mass
337.190260
SMILES
C1CC(CCC1NC2=NC=NC3=C2C=C(C=C3)C#N)N4CCOCC4
InChI
InChI=1S/C19H23N5O/c20-12-14-1-6-18-17(11-14)19(22-13-21-18)23-15-2-4-16(5-3-15)24-7-9-25-10-8-24/h1,6,11,13,15-16H,2-5,7-10H2,(H,21,22,23)
InChIKey
HVQXFGHHSFTACS-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
25
Aromatic heavy atom count
10
Fraction Csp3
0.53
Rotatable bonds
3
H-bond acceptors
6
H-bond donors
1
Molar refractivity
96.31
TPSA
74.07
LogP / Solubility
WLOGP
2.56
MLOGP
2.27
XLogP3
2.6
Consensus LogP
2.48
Log S (ESOL)
-3.64
Class (ESOL)
Poorly soluble
Log S (Ali)
-4.17
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-4.34
Class (SILICOS-IT)
Slightly soluble
ADME
GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-2.96
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
Yes
Synthetic Accessibility
3
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