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CAS 18055-70-4 1,3-Di(p-tolyl)-1,1,3,3-tetramethyldisiloxane molecular structure lightbox
CAS RN: 18055-70-4

1,3-Di(p-tolyl)-1,1,3,3-tetramethyldisiloxane

Product Availability

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1 package records0 with current stock1 grade group
Batch No.PackageAvailabilityLead TimeInquiry
Batchno.20251120 1g Out of stock 15 business days Inquiry
  • Product code: starshine_CAS18055-70-4
  • Purity/Analytical Methods: >99.0%
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18055-70-4 / [dimethyl-(4-methylphenyl)silyl]oxy-dimethyl-(4-methylphenyl)silane

Standard CAS: 18055-70-4 Multi CAS: No
Basic Information Computed Properties

Basic Information

CAS
18055-70-4
Multi CAS
No
Molecular Formula
C18H26OSi2
Molecular Weight
314.600000
Exact Mass
314.152219
SMILES
CC1=CC=C(C=C1)[Si](C)(C)O[Si](C)(C)C2=CC=C(C=C2)C
InChI
InChI=1S/C18H26OSi2/c1-15-7-11-17(12-8-15)20(3,4)19-21(5,6)18-13-9-16(2)10-14-18/h7-14H,1-6H3
InChIKey
MEQYEVSZYLVDNX-UHFFFAOYSA-N

Computed Properties

Structural Parameters

Heavy atom count
21
Aromatic heavy atom count
12
Fraction Csp3
0.33
Rotatable bonds
4
H-bond acceptors
1
Molar refractivity
97.68
TPSA
9.23

LogP / Solubility

WLOGP
3.84
MLOGP
3.4
XLogP3
3.84
Consensus LogP
3.69
Log S (ESOL)
-4.37
Class (ESOL)
Slightly soluble
Log S (Ali)
-4.92
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-5.38
Class (SILICOS-IT)
Slightly soluble

ADME

GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-1.91

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
2.5

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