CAS RN: 168154-76-5
Carfilzomib Related Impurity
Product Availability
Choose a grade to view its available package options.
1 package records0 with current stock1 grade group
| Batch No. | Package | Availability | Lead Time | Inquiry |
|---|---|---|---|---|
| Batchno.20250816 | 100mg / 250mg / 1g | Out of stock | 5-7 business days | Inquiry |
- Product code: starshine_CAS168154-76-5
- Purity/Analytical Methods: >99.0%
168154-76-5 / (2S)-2-amino-4-oxo-4-phenylbutanoic acid;hydrochloride
Basic Information
CAS
168154-76-5
Multi CAS
No
Molecular Formula
C10H12ClNO3
Molecular Weight
229.660000
Exact Mass
229.050571
SMILES
C1=CC=C(C=C1)C(=O)C[C@@H](C(=O)O)N.Cl
InChI
InChI=1S/C10H11NO3.ClH/c11-8(10(13)14)6-9(12)7-4-2-1-3-5-7;/h1-5,8H,6,11H2,(H,13,14);1H/t8-;/m0./s1
InChIKey
QSZYKVGEOKNNOP-QRPNPIFTSA-N
Computed Properties
Structural Parameters
Heavy atom count
15
Aromatic heavy atom count
6
Fraction Csp3
0.2
Rotatable bonds
4
H-bond acceptors
3
H-bond donors
2
Molar refractivity
58.25
TPSA
80.39
LogP / Solubility
WLOGP
1.09
MLOGP
0.97
XLogP3
1.09
Consensus LogP
1.05
Log S (ESOL)
-1.98
Class (ESOL)
Soluble
Log S (Ali)
-2.23
Class (Ali)
Moderately soluble
Log S (SILICOS-IT)
-2.54
Class (SILICOS-IT)
Moderately soluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-3.34
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
2
Safety & Transport
Pictogram(s)
Irritant
Signal
Warning
GHS Hazard Statements
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Precautionary Statement Codes
P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501
Customers Also Viewed
-
![CAS 168161-71-5 Urea, N-[1-(3,3-dimethyl-2-oxobutyl)-2,3-dihydro-2-oxo-5-(2-pyridinyl)-1H-1,4-benzodiazepin-3-yl]-N’-[3-(methylamino)phenyl]- molecular structure](data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%200%200'%3E%3C/svg%3E)
Urea, N-[1-(3,3-dimethyl-2-oxobutyl)-2,3-dihydro-2-oxo-5-(2-pyridinyl)-1H-1,4-benzodiazepin-3-yl]-N’-[3-(methylamino)phenyl]-
- CAS RN: 168161-71-5
- Product Code: starshine_CAS168161-71-5
- Purity/Analytical method: >99.0%
-
3-(N-TERT-BUTOXYCARBONYL-N-METHYLAMINO)BENZOIC ACID
- CAS RN: 168162-30-9
- Product Code: SSC-073320
-
-
4-Desmethoxypropoxyl-4-chloro Rabeprazole
- CAS RN: 168167-42-8
- Product Code: starshine_CAS168167-42-8
- Purity/Analytical method: >99.0%
-
TERT-BUTYL 4-BROMONAPHTHALEN-1-YLCARBAMATE
- CAS RN: 168169-11-7
- Product Code: starshine_CAS168169-11-7
- Purity/Analytical method: >99.0%
-
(E)-3-(3-(cyclopentyloxy)-4-methoxyphenyl)-2-methylacrylic acid
- CAS RN: 168169-98-0
- Product Code: starshine_CAS168169-98-0
- Purity/Analytical method: >99.0%
![CAS 168161-71-5 Urea, N-[1-(3,3-dimethyl-2-oxobutyl)-2,3-dihydro-2-oxo-5-(2-pyridinyl)-1H-1,4-benzodiazepin-3-yl]-N’-[3-(methylamino)phenyl]- molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/168161-71-5.gif)
