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CAS 1677-44-7 2-hydroxy-6-methyl-1H-quinolin-4-one molecular structure lightbox
CAS RN: 1677-44-7

2-hydroxy-6-methyl-1H-quinolin-4-one

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5 package records1 with current stock1 grade group
Batch No.PackageAvailabilityWarehouseLead TimeInquiry
Batchno.20250828 100mg In stock Shanghai Inquiry
Batchno.20251023 1g Out of stock Inquiry
Batchno.20260116 250mg Out of stock Inquiry
Batchno.20250209 50mg / 250mg Out of stock 8-10 business days Inquiry
Batchno.20260130 5g Out of stock Inquiry
  • Product code: starshine_CAS1677-44-7
  • Purity/Analytical Methods: >99.0%
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1677-44-7 / 4-hydroxy-6-methyl-1H-quinolin-2-one

Standard CAS: 1677-44-7 Multi CAS: No
Basic Information Computed Properties

Basic Information

CAS
1677-44-7
Multi CAS
No
Molecular Formula
C10H9NO2
Molecular Weight
175.180000
Exact Mass
175.063329
SMILES
CC1=CC2=C(C=C1)NC(=O)C=C2O
InChI
InChI=1S/C10H9NO2/c1-6-2-3-8-7(4-6)9(12)5-10(13)11-8/h2-5H,1H3,(H2,11,12,13)
InChIKey
OXSZQTDCCMODLE-UHFFFAOYSA-N

Computed Properties

Structural Parameters

Heavy atom count
13
Aromatic heavy atom count
10
Fraction Csp3
0.1
H-bond acceptors
2
H-bond donors
2
Molar refractivity
50.97
TPSA
53.09

LogP / Solubility

WLOGP
1.54
MLOGP
1.35
XLogP3
1.1
Consensus LogP
1.33
Log S (ESOL)
-2.47
Class (ESOL)
Moderately soluble
Log S (Ali)
-2.11
Class (Ali)
Moderately soluble
Log S (SILICOS-IT)
-2.08
Class (SILICOS-IT)
Moderately soluble

ADME

GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-2.69

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
No
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
1.5

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