[email protected]
CAS 164656-23-9 Dutasteride molecular structure lightbox
CAS RN: 164656-23-9

Dutasteride

Product Availability

Choose a grade to view its available package options.

12 package records12 with current stock3 grade groups
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20250331 10g In stock Shandong Inquiry
Batchno.20250705 250mg In stock Shanghai, Shandong, Guangdong Inquiry
Batchno.20251012 2g In stock Chongqing Inquiry
Batchno.20260508 500mg In stock Shanghai, Shandong, Chongqing Inquiry
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20250530 100mg In stock Inquiry
Batchno.20251012 10mg In stock Inquiry
Batchno.20260111 1g In stock Inquiry
Batchno.20250726 250mg In stock Inquiry
Batchno.20250405 500mg In stock Inquiry
Batchno.20250627 50mg In stock Inquiry
Batchno.20250105 5g In stock Inquiry
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20260613 1ml In stock Inquiry
  • Product code: ICTD5973
  • Purity/Analytical Methods: >98.0%(HPLC)
GET A QUOTE

164656-23-9 / (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-[2,5-bis(trifluoromethyl)phenyl]-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide

Standard CAS: 164656-23-9 Multi CAS: No
Basic Information Physical Properties Computed Properties Safety & Transport

Basic Information

CAS
164656-23-9
Multi CAS
No
Molecular Formula
C27H30F6N2O2
Molecular Weight
528.500000
Exact Mass
528.221147
SMILES
C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2C(=O)NC4=C(C=CC(=C4)C(F)(F)F)C(F)(F)F)CC[C@@H]5[C@@]3(C=CC(=O)N5)C
InChI
InChI=1S/C27H30F6N2O2/c1-24-11-9-17-15(4-8-21-25(17,2)12-10-22(36)35-21)16(24)6-7-19(24)23(37)34-20-13-14(26(28,29)30)3-5-18(20)27(31,32)33/h3,5,10,12-13,15-17,19,21H,4,6-9,11H2,1-2H3,(H,34,37)(H,35,36)/t15-,16-,17-,19+,21+,24-,25+/m0/s1
InChIKey
JWJOTENAMICLJG-QWBYCMEYSA-N

Physical Properties

Melting Point
242-250
Physical Description
Solid
State
Solid

Computed Properties

Structural Parameters

Heavy atom count
37
Aromatic heavy atom count
6
Fraction Csp3
0.63
Rotatable bonds
2
H-bond acceptors
2
H-bond donors
2
Molar refractivity
124.02
TPSA
58.2

LogP / Solubility

WLOGP
6.58
MLOGP
5.83
XLogP3
5.4
Consensus LogP
5.94
Log S (ESOL)
-7.25
Class (ESOL)
Insoluble
Log S (Ali)
-8.64
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-8.79
Class (SILICOS-IT)
Insoluble

ADME

GI absorption
Low
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-1.28

Drug-likeness / Medicinal Chemistry

Lipinski
No
Ghose
No
Veber
Yes
Egan
No
Muegge
No
Bioavailability score
0.17
Leadlikeness
No
Synthetic Accessibility
8.5

Safety & Transport

Pictogram(s)
Health Hazard Environmental Hazard
Signal
Danger
GHS Hazard Statements
H351 (15.8%): Suspected of causing cancer [Warning Carcinogenicity] H360 (84.2%): May damage fertility or the unborn child [Danger Reproductive toxicity] H360FD (10.5%): May damage fertility; May damage the unborn child [Danger Reproductive toxicity] H410 (31.6%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] H412 (52.6%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]
Precautionary Statement Codes
P203, P273, P280, P318, P391, P405, and P501

Customers Also Viewed

Get In Touch

Contact Us