CAS RN: 1633009-87-6
BI 689648
Product Availability
Choose a grade to view its available package options.
1 package records0 with current stock1 grade group
| Batch No. | Package | Availability | Lead Time | Inquiry |
|---|---|---|---|---|
| Batchno.20251118 | 1mg / 5mg | Out of stock | 5-7 business days | Inquiry |
- Product code: starshine_CAS1633009-87-6
- Purity/Analytical Methods: >99.0%
1633009-87-6 / 6-[5-(methoxymethyl)-3-pyridinyl]-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide
Basic Information
CAS
1633009-87-6
Multi CAS
No
Molecular Formula
C16H18N4O2
Molecular Weight
298.340000
Exact Mass
298.142976
SMILES
COCC1=CC(=CN=C1)C2=CC3=C(N=C2)N(CCC3)C(=O)N
InChI
InChI=1S/C16H18N4O2/c1-22-10-11-5-13(8-18-7-11)14-6-12-3-2-4-20(16(17)21)15(12)19-9-14/h5-9H,2-4,10H2,1H3,(H2,17,21)
InChIKey
DJFDCVNQDFICKV-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
22
Aromatic heavy atom count
12
Fraction Csp3
0.31
Rotatable bonds
3
H-bond acceptors
4
H-bond donors
1
Molar refractivity
83.43
TPSA
81.34
LogP / Solubility
WLOGP
2.12
MLOGP
1.88
XLogP3
0.6
Consensus LogP
1.53
Log S (ESOL)
-3.23
Class (ESOL)
Poorly soluble
Log S (Ali)
-3.54
Class (Ali)
Poorly soluble
Log S (SILICOS-IT)
-3.72
Class (SILICOS-IT)
Poorly soluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-3.03
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
Yes
Synthetic Accessibility
2.5
Customers Also Viewed
-
FIIN-2
- CAS RN: 1633044-56-0
- Product Code: starshine_CAS1633044-56-0
- Purity/Analytical method: >99.0%
-
2-(4-phenoxyphenyl)-7-(piperidin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide
- CAS RN: 1633350-04-5
- Product Code: SSC-070969
-
7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide
- CAS RN: 1633350-06-7
- Product Code: SSC-070970
-
1-Iminothiomorpholine 1-Oxide Hydrochloride
- CAS RN: 1633667-60-3
- Product Code: SSC-070977
-
(6-fluoroimidazo[1,2-a]pyridin-3-yl)(phenyl)methanone
- CAS RN: 1634647-80-5
- Product Code: starshine_CAS1634647-80-5
- Purity/Analytical method: >99.0%
-
(R)-(-)-2-Pyrrolidinemethanol hydrochloride
- CAS RN: 1635389-95-5
- Product Code: SSC-071040
![CAS 1633350-04-5 2-(4-phenoxyphenyl)-7-(piperidin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1633350-04-5.gif)
![CAS 1633350-06-7 7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1633350-06-7.gif)
![CAS 1634647-80-5 (6-fluoroimidazo[1,2-a]pyridin-3-yl)(phenyl)methanone molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1634647-80-5.gif)
