CAS RN: 1587705-63-2
INH154
Product Availability
Choose a grade to view its available package options.
1 package records0 with current stock1 grade group
| Batch No. | Package | Availability | Inquiry |
|---|---|---|---|
| Batchno.20251112 | 5mg | Out of stock | Inquiry |
- Product code: starshine_CAS1587705-63-2
- Purity/Analytical Methods: >99.0%
1587705-63-2 / N-[4-(2,6-dimethyl-4-piperidin-1-ylphenyl)-1,3-thiazol-2-yl]pyridine-4-carboxamide
Basic Information
CAS
1587705-63-2
Multi CAS
No
Molecular Formula
C22H24N4OS
Molecular Weight
392.500000
Exact Mass
392.167083
SMILES
CC1=CC(=CC(=C1C2=CSC(=N2)NC(=O)C3=CC=NC=C3)C)N4CCCCC4
InChI
InChI=1S/C22H24N4OS/c1-15-12-18(26-10-4-3-5-11-26)13-16(2)20(15)19-14-28-22(24-19)25-21(27)17-6-8-23-9-7-17/h6-9,12-14H,3-5,10-11H2,1-2H3,(H,24,25,27)
InChIKey
BBVORAZSFSZSKG-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
28
Aromatic heavy atom count
17
Fraction Csp3
0.32
Rotatable bonds
4
H-bond acceptors
5
H-bond donors
1
Molar refractivity
115.28
TPSA
58.12
LogP / Solubility
WLOGP
5.06
MLOGP
4.48
XLogP3
4.4
Consensus LogP
4.65
Log S (ESOL)
-5.65
Class (ESOL)
Slightly soluble
Log S (Ali)
-6.44
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-6.9
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-1.52
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
No
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
3
Customers Also Viewed
-
![CAS 1587727-31-8 2-((S)-1-((2S,5R)-5-(4-CHLORO-5-FLUORO-2-(TRIFLUOROMETHYL)PHENYL)TETRAHYDROFURAN-2-YL)ETHYL)-7-(4-METHYL-1H-IMIDAZOL-1-YL)-3,4-DIHYDRO-2H-PYRIDO[1,2-A]PYRAZINE-1,6-DIONE molecular structure](data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%200%200'%3E%3C/svg%3E)
2-((S)-1-((2S,5R)-5-(4-CHLORO-5-FLUORO-2-(TRIFLUOROMETHYL)PHENYL)TETRAHYDROFURAN-2-YL)ETHYL)-7-(4-METHYL-1H-IMIDAZOL-1-YL)-3,4-DIHYDRO-2H-PYRIDO[1,2-A]PYRAZINE-1,6-DIONE
- CAS RN: 1587727-31-8
- Product Code: starshine_CAS1587727-31-8
- Purity/Analytical method: >99.0%
-
4-AMino-1,2-dihydroisoquinolin-3(4H)-one dihydrobroMide
- CAS RN: 1588440-86-1
- Product Code: SSC-067007
-
-
10-(Phosphonooxy)decyl methacrylate
- CAS RN: 1588440-89-4
- Product Code: starshine_CAS1588440-89-4
- Purity/Analytical method: >99.0%
-
-
4,7-DibroMo-2-phenylbenzo[d]thiazole
- CAS RN: 1588440-95-2
- Product Code: starshine_CAS1588440-95-2
- Purity/Analytical method: >99.0%
![CAS 1587727-31-8 2-((S)-1-((2S,5R)-5-(4-CHLORO-5-FLUORO-2-(TRIFLUOROMETHYL)PHENYL)TETRAHYDROFURAN-2-YL)ETHYL)-7-(4-METHYL-1H-IMIDAZOL-1-YL)-3,4-DIHYDRO-2H-PYRIDO[1,2-A]PYRAZINE-1,6-DIONE molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1587727-31-8.gif)
![CAS 1588440-95-2 4,7-DibroMo-2-phenylbenzo[d]thiazole molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/CB62672849.gif)