CAS RN: 1581270-11-2
RIP2 kinase inhibitor 2
Product Availability
Choose a grade to view its available package options.
1 package records0 with current stock1 grade group
| Batch No. | Package | Availability | Lead Time | Inquiry |
|---|---|---|---|---|
| Batchno.20251110 | 1mg / 5mg | Out of stock | 5-7 business days | Inquiry |
- Product code: starshine_CAS1581270-11-2
- Purity/Analytical Methods: >99.0%
1581270-11-2 / 6-tert-butylsulfonyl-N-(4,5-dimethyl-1H-pyrazol-3-yl)-7-(2-methoxyethoxy)quinolin-4-amine
Basic Information
CAS
1581270-11-2
Multi CAS
No
Molecular Formula
C21H28N4O4S
Molecular Weight
432.500000
Exact Mass
432.183127
SMILES
CC1=C(NN=C1NC2=C3C=C(C(=CC3=NC=C2)OCCOC)S(=O)(=O)C(C)(C)C)C
InChI
InChI=1S/C21H28N4O4S/c1-13-14(2)24-25-20(13)23-16-7-8-22-17-12-18(29-10-9-28-6)19(11-15(16)17)30(26,27)21(3,4)5/h7-8,11-12H,9-10H2,1-6H3,(H2,22,23,24,25)
InChIKey
QODPGRHWJBWTJC-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
30
Aromatic heavy atom count
15
Fraction Csp3
0.43
Rotatable bonds
7
H-bond acceptors
7
H-bond donors
2
Molar refractivity
117.4
TPSA
106.2
LogP / Solubility
WLOGP
3.92
MLOGP
3.47
XLogP3
3.2
Consensus LogP
3.53
Log S (ESOL)
-4.9
Class (ESOL)
Slightly soluble
Log S (Ali)
-5.93
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-6.56
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-2.58
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
2.5
Customers Also Viewed
-
![CAS 1581276-63-2 (3beta,4alpha,16beta,21beta,22alpha)-Olean-12-ene-3,16,21,22,23,28-hexol 21-[(2E)-2-methyl-2-butenoate] molecular structure](data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%200%200'%3E%3C/svg%3E)
(3beta,4alpha,16beta,21beta,22alpha)-Olean-12-ene-3,16,21,22,23,28-hexol 21-[(2E)-2-methyl-2-butenoate]
- CAS RN: 1581276-63-2
- Product Code: starshine_CAS1581276-63-2
- Purity/Analytical method: >99.0%
-
-
(2′-Methylamino-1,1′-biphenyl-2-yl)methanesulfonatopalladium(II) dimer
- CAS RN: 1581285-85-9
- Product Code: SSC-066690
-
tertbutyl 5oxo2azaspiro[3.4]octane2carboxylate
- CAS RN: 1581683-57-9
- Product Code: SSC-066700
-
Methiocarb-d3
- CAS RN: 1581694-94-1
- Product Code: starshine_CAS1581694-94-1
- Purity/Analytical method: >99.0%
-
2,3-Thiophenedicarboxylic acid, 4-[(phenoxycarbonyl)amino]-, 2,3-dimethyl ester
- CAS RN: 1581731-15-8
- Product Code: SSC-066704
![CAS 1581276-63-2 (3beta,4alpha,16beta,21beta,22alpha)-Olean-12-ene-3,16,21,22,23,28-hexol 21-[(2E)-2-methyl-2-butenoate] molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1581276-63-2.gif)
![CAS 1581683-57-9 tertbutyl 5oxo2azaspiro[3.4]octane2carboxylate molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/CB22704803.gif)
![CAS 1581731-15-8 2,3-Thiophenedicarboxylic acid, 4-[(phenoxycarbonyl)amino]-, 2,3-dimethyl ester molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1581731-15-8.gif)