CAS RN: 148849-67-6
Ivabradine Hydrochloride
Product Availability
Choose a grade to view its available package options.
8 package records7 with current stock1 grade group
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20251122 | 100mg | In stock | Shanghai, Shenzhen | Inquiry |
| Batchno.20251210 | 10mg | In stock | Shanghai, Tianjin, Wuhan | Inquiry |
| Batchno.20251108 | 1g | Out of stock | Inquiry | |
| Batchno.20250507 | 1mg | In stock | Shanghai, Tianjin, Wuhan | Inquiry |
| Batchno.20251209 | 250mg | In stock | Shanghai, Shenzhen, Tianjin | Inquiry |
| Batchno.20251013 | 250mg / 1g | Confirm by inquiry | Shanghai | Inquiry |
| Batchno.20260623 | 50mg | In stock | Shanghai, Tianjin | Inquiry |
| Batchno.20251225 | 5g | In stock | Tianjin, Chengdu | Inquiry |
- Product code: SSC-059000
Historical Factory Record
Historical Supply Reference
This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.
- Pack sizes on record: 1g
- Available purity: ≥95%
- Inventory rows with stock: 0
- Bulk packaging: confirmed by inquiry
Reference Pack Sizes
Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.
| Pack Size | Recorded Purity | Available Qty | Ship From | Inquiry |
|---|---|---|---|---|
| 1g | ≥95% | 0 Out of Stock | Shanghai | Inquiry |
148849-67-6 / 3-[3-[[(7S)-3,4-dimethoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methylamino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one;hydrochloride
Basic Information
CAS
148849-67-6
Multi CAS
No
Molecular Formula
C27H37ClN2O5
Molecular Weight
505.000000
Exact Mass
504.239100
SMILES
CN(CCCN1CCC2=CC(=C(C=C2CC1=O)OC)OC)C[C@H]3CC4=CC(=C(C=C34)OC)OC.Cl
InChI
InChI=1S/C27H36N2O5.ClH/c1-28(17-21-11-20-14-25(33-4)26(34-5)16-22(20)21)8-6-9-29-10-7-18-12-23(31-2)24(32-3)13-19(18)15-27(29)30;/h12-14,16,21H,6-11,15,17H2,1-5H3;1H/t21-;/m1./s1
InChIKey
HLUKNZUABFFNQS-ZMBIFBSDSA-N
Computed Properties
Structural Parameters
Heavy atom count
35
Aromatic heavy atom count
12
Fraction Csp3
0.52
Rotatable bonds
10
H-bond acceptors
6
H-bond donors
1
Molar refractivity
138.89
TPSA
60.47
LogP / Solubility
WLOGP
3.73
MLOGP
3.32
XLogP3
3.73
Consensus LogP
3.59
Log S (ESOL)
-4.92
Class (ESOL)
Slightly soluble
Log S (Ali)
-6.4
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-7.24
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-3.15
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
3.5
Safety & Transport
Pictogram(s)
Irritant
Health Hazard
Environmental Hazard
Signal
Danger
GHS Hazard Statements
H302 (14.6%): Harmful if swallowed [Warning Acute toxicity, oral]
H360 (12.5%): May damage fertility or the unborn child [Danger Reproductive toxicity]
H373 (12.5%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]
H400 (85.4%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]
Precautionary Statement Codes
P203, P260, P264, P270, P273, P280, P301+P317, P318, P319, P330, P391, P405, and P501
