CAS RN: 1448895-09-7
ML314
Product Availability
Choose a grade to view its available package options.
7 package records6 with current stock1 grade group
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20260509 | 100mg | In stock | Shanghai | Inquiry |
| Batchno.20260415 | 10mg | In stock | Shanghai | Inquiry |
| Batchno.20250720 | 250mg | Out of stock | Inquiry | |
| Batchno.20251211 | 25mg | In stock | Shanghai | Inquiry |
| Batchno.20250729 | 2mg | In stock | Shanghai | Inquiry |
| Batchno.20250428 | 50mg | In stock | Shanghai | Inquiry |
| Batchno.20260525 | 5mg | In stock | Shanghai | Inquiry |
- Product code: starshine_CAS1448895-09-7
- Purity/Analytical Methods: >99.0%
1448895-09-7 / 2-cyclopropyl-6,7-dimethoxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]quinazoline
Basic Information
CAS
1448895-09-7
Multi CAS
No
Molecular Formula
C24H28N4O3
Molecular Weight
420.500000
Exact Mass
420.216141
SMILES
COC1=CC=CC=C1N2CCN(CC2)C3=NC(=NC4=CC(=C(C=C43)OC)OC)C5CC5
InChI
InChI=1S/C24H28N4O3/c1-29-20-7-5-4-6-19(20)27-10-12-28(13-11-27)24-17-14-21(30-2)22(31-3)15-18(17)25-23(26-24)16-8-9-16/h4-7,14-16H,8-13H2,1-3H3
InChIKey
SWEOAXMICIJCQC-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
31
Aromatic heavy atom count
16
Fraction Csp3
0.42
Rotatable bonds
6
H-bond acceptors
7
Molar refractivity
122.04
TPSA
59.95
LogP / Solubility
WLOGP
3.86
MLOGP
3.42
XLogP3
4.1
Consensus LogP
3.79
Log S (ESOL)
-4.86
Class (ESOL)
Slightly soluble
Log S (Ali)
-5.79
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-6.32
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-2.54
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
3.5
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