CAS RN: 1442472-39-0
Ripretinib
Product Availability
Choose a grade to view its available package options.
1 package records1 with current stock1 grade group
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20251203 | 1mg / 5mg / 25mg / 100mg | Confirm by inquiry | Shanghai | Inquiry |
- Product code: SSC-055454
Historical Factory Record
Historical Supply Reference
This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.
- Pack sizes on record: 1g
- Available purity: ≥95%
- Inventory rows with stock: 0
- Bulk packaging: confirmed by inquiry
Reference Pack Sizes
Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.
| Pack Size | Recorded Purity | Available Qty | Ship From | Inquiry |
|---|---|---|---|---|
| 1g | ≥95% | 0 Out of Stock | Hong Kong | Inquiry |
1442472-39-0 / 1-[4-bromo-5-[1-ethyl-7-(methylamino)-2-oxo-1,6-naphthyridin-3-yl]-2-fluorophenyl]-3-phenylurea
Basic Information
CAS
1442472-39-0
Multi CAS
No
Molecular Formula
C24H21BrFN5O2
Molecular Weight
510.400000
Exact Mass
509.086270
SMILES
CCN1C2=CC(=NC=C2C=C(C1=O)C3=CC(=C(C=C3Br)F)NC(=O)NC4=CC=CC=C4)NC
InChI
InChI=1S/C24H21BrFN5O2/c1-3-31-21-12-22(27-2)28-13-14(21)9-17(23(31)32)16-10-20(19(26)11-18(16)25)30-24(33)29-15-7-5-4-6-8-15/h4-13H,3H2,1-2H3,(H,27,28)(H2,29,30,33)
InChIKey
CEFJVGZHQAGLHS-UHFFFAOYSA-N
Physical Properties
Boiling Point
568.6±50.0
Computed Properties
Structural Parameters
Heavy atom count
33
Aromatic heavy atom count
22
Fraction Csp3
0.12
Rotatable bonds
5
H-bond acceptors
5
H-bond donors
3
Molar refractivity
133.4
TPSA
88.05
LogP / Solubility
WLOGP
5.67
MLOGP
5.03
XLogP3
4.1
Consensus LogP
4.93
Log S (ESOL)
-6.74
Class (ESOL)
Insoluble
Log S (Ali)
-7.84
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-8.28
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
Low
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-1.81
Drug-likeness / Medicinal Chemistry
Lipinski
No
Ghose
No
Veber
Yes
Egan
Yes
Muegge
No
Bioavailability score
0.56
Leadlikeness
No
Synthetic Accessibility
3
Safety & Transport
GHS Hazard Statements
Not Classified
Reported as not meeting GHS hazard criteria by 1 of 1 companies. For more detailed information, please visit ECHA C&L website.
Customers Also Viewed
-
![CAS 1442483-69-3 3-Piperidinepropanoic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]-2-oxo-, methyl ester, (αS,3S)- molecular structure](data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%200%200'%3E%3C/svg%3E)
3-Piperidinepropanoic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]-2-oxo-, methyl ester, (αS,3S)-
- CAS RN: 1442483-69-3
- Product Code: SSC-055457
-
8H-Indeno[1,2-d]oxazole-2-acetonitrile, α-[(3aS,8aR)-3a,8a-dihydro-8H-indeno[1,2-d]oxazol-2-yl]-3a,8a-dihydro-, (3aS,8aR)-
- CAS RN: 1442644-14-5
- Product Code: starshine_CAS1442644-14-5
- Purity/Analytical method: >99.0%
-
(S)-3,3′-Bis(3,5-di-tert-butylphenyl)-1,1′-binapthyl-2,2′-diyl hydrogenphosphate
- CAS RN: 1442645-05-7
- Product Code: starshine_CAS1442645-05-7
- Purity/Analytical method: >99.0%
-
-
Methyl 3-[Bis[3-(Boc-amino)propyl]amino]propanoate
- CAS RN: 1442656-30-5
- Product Code: SSC-055465
-
![CAS 1442483-69-3 3-Piperidinepropanoic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]-2-oxo-, methyl ester, (αS,3S)- molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1442483-69-3.gif)
![CAS 1442644-14-5 8H-Indeno[1,2-d]oxazole-2-acetonitrile, α-[(3aS,8aR)-3a,8a-dihydro-8H-indeno[1,2-d]oxazol-2-yl]-3a,8a-dihydro-, (3aS,8aR)- molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1442644-14-5.gif)
![CAS 1442648-14-7 8-bromodibenzo[b,d]furan-2-carbonitrile molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1442648-14-7.gif)
![CAS 1442656-30-5 Methyl 3-[Bis[3-(Boc-amino)propyl]amino]propanoate molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1442656-30-5.gif)
