![CAS 1434288-24-0 2-((1H-benzo[d]imidazol-1-yl)methyl)-6-methyl-4H-pyrido[1,2-a]pyrimidin-4-one molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1434288-24-0.gif)
CAS RN: 1434288-24-0
2-((1H-benzo[d]imidazol-1-yl)methyl)-6-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
Product Availability
Choose a grade to view its available package options.
5 package records0 with current stock2 grade groups
| Batch No. | Package | Availability | Lead Time | Inquiry |
|---|---|---|---|---|
| Batchno.20260103 | 100mg / 250mg / 1g | Out of stock | 8-10 business days | Inquiry |
- Product code: starshine_CAS1434288-24-0
- Purity/Analytical Methods: >99.0%
1434288-24-0 / 2-(benzimidazol-1-ylmethyl)-6-methylpyrido[1,2-a]pyrimidin-4-one
Basic Information
CAS
1434288-24-0
Multi CAS
No
Molecular Formula
C17H14N4O
Molecular Weight
290.320000
Exact Mass
290.116761
SMILES
CC1=CC=CC2=NC(=CC(=O)N12)CN3C=NC4=CC=CC=C43
InChI
InChI=1S/C17H14N4O/c1-12-5-4-8-16-19-13(9-17(22)21(12)16)10-20-11-18-14-6-2-3-7-15(14)20/h2-9,11H,10H2,1H3
InChIKey
ICTBPKWPCGSFPZ-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
22
Aromatic heavy atom count
19
Fraction Csp3
0.12
Rotatable bonds
2
H-bond acceptors
5
Molar refractivity
85.03
TPSA
52.19
LogP / Solubility
WLOGP
2.4
MLOGP
2.12
XLogP3
1.6
Consensus LogP
2.04
Log S (ESOL)
-3.66
Class (ESOL)
Poorly soluble
Log S (Ali)
-3.67
Class (Ali)
Poorly soluble
Log S (SILICOS-IT)
-3.78
Class (SILICOS-IT)
Poorly soluble
ADME
GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-2.79
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
Yes
Synthetic Accessibility
3
Safety & Transport
Pictogram(s)
Irritant
Signal
Warning
GHS Hazard Statements
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Precautionary Statement Codes
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501
Customers Also Viewed
-
2-Amino-3-bromo-5-trifluoromethyl-benzoic acid
- CAS RN: 1434631-44-3
- Product Code: SSC-054905
-
-
Thieno[2,3-d]pyrimidine-3(2H)-acetic acid, 6-bromo-1,4-dihydro-α,α,5-trimethyl-2,4-dioxo-, 1,1-dimethylethyl ester
- CAS RN: 1434643-33-0
- Product Code: SSC-054907
-
2-(2-methoxyphenyl)-2-((tetrahydro-2H-pyran-4-yl)oxy)ethan-1-ol
- CAS RN: 1434652-62-6
- Product Code: SSC-054908
-
(R)-2-(2-methoxyphenyl)-2-((tetrahydro-2H-pyran-4-yl)oxy)ethan-1-ol
- CAS RN: 1434652-66-0
- Product Code: SSC-054909
-
1H-Pyrrolo[2,3-b]pyridine-5-carbonitrile, 1-[(4-methylphenyl)sulfonyl]-3-(4,4,5,5-tetramethyl-1,3,2-
- CAS RN: 1434747-57-5
- Product Code: SSC-054921
![CAS 1434643-33-0 Thieno[2,3-d]pyrimidine-3(2H)-acetic acid, 6-bromo-1,4-dihydro-α,α,5-trimethyl-2,4-dioxo-, 1,1-dimethylethyl ester molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1434643-33-0.gif)
![CAS 1434747-57-5 1H-Pyrrolo[2,3-b]pyridine-5-carbonitrile, 1-[(4-methylphenyl)sulfonyl]-3-(4,4,5,5-tetramethyl-1,3,2- molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1434747-57-5.gif)