CAS RN: 142326-59-8
L-701,324
Product Availability
Choose a grade to view its available package options.
8 package records4 with current stock2 grade groups
| Batch No. | Package | Availability | Warehouse | Lead Time | Inquiry |
|---|---|---|---|---|---|
| Batchno.20250715 | 10mg / 50mg | Out of stock | 5-7 business days | Inquiry |
| Batch No. | Package | Availability | Warehouse | Lead Time | Inquiry |
|---|---|---|---|---|---|
| Batchno.20250501 | 100mg | Out of stock | Inquiry | ||
| Batchno.20251118 | 10mg | In stock | Shanghai | Inquiry | |
| Batchno.20250212 | 1g | Out of stock | Inquiry | ||
| Batchno.20260406 | 1mg | In stock | Shanghai, Tianjin | Inquiry | |
| Batchno.20250827 | 250mg | Out of stock | Inquiry | ||
| Batchno.20250121 | 25mg | In stock | Wuhan | Inquiry | |
| Batchno.20250511 | 50mg | In stock | Shanghai | Inquiry |
- Product code: starshine_CAS142326-59-8
- Purity/Analytical Methods: >99.0%
142326-59-8 / 7-chloro-4-hydroxy-3-(3-phenoxyphenyl)-1H-quinolin-2-one
Basic Information
CAS
142326-59-8
Multi CAS
No
Molecular Formula
C21H14ClNO3
Molecular Weight
363.800000
Exact Mass
363.066221
SMILES
C1=CC=C(C=C1)OC2=CC=CC(=C2)C3=C(C4=C(C=C(C=C4)Cl)NC3=O)O
InChI
InChI=1S/C21H14ClNO3/c22-14-9-10-17-18(12-14)23-21(25)19(20(17)24)13-5-4-8-16(11-13)26-15-6-2-1-3-7-15/h1-12H,(H2,23,24,25)
InChIKey
FLVRDMUHUXVRET-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
26
Aromatic heavy atom count
22
Rotatable bonds
3
H-bond acceptors
3
H-bond donors
2
Molar refractivity
103.2
TPSA
62.32
LogP / Solubility
WLOGP
5.35
MLOGP
4.72
XLogP3
4.5
Consensus LogP
4.86
Log S (ESOL)
-5.89
Class (ESOL)
Slightly soluble
Log S (Ali)
-6.4
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-6.82
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
No
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-1.14
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
No
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
3
Safety & Transport
Pictogram(s)
Irritant
Signal
Warning
GHS Hazard Statements
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Precautionary Statement Codes
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501
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