![CAS 142283-66-7 1-Azaspiro[4.5]decane-2,8-dione, 1-Methyl- molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/142283-66-7.gif)
CAS RN: 142283-66-7
1-Azaspiro[4.5]decane-2,8-dione, 1-Methyl-
Product Availability
Choose a grade to view its available package options.
1 package records0 with current stock1 grade group
| Batch No. | Package | Availability | Lead Time | Inquiry |
|---|---|---|---|---|
| Batchno.20260304 | 100mg | Out of stock | 1 business days | Inquiry |
- Product code: starshine_CAS142283-66-7
- Purity/Analytical Methods: >99.0%
142283-66-7 / 1-methyl-1-azaspiro[4.5]decane-2,8-dione
Basic Information
CAS
142283-66-7
Multi CAS
No
Molecular Formula
C10H15NO2
Molecular Weight
181.230000
Exact Mass
181.110279
SMILES
CN1C(=O)CCC12CCC(=O)CC2
InChI
InChI=1S/C10H15NO2/c1-11-9(13)4-7-10(11)5-2-8(12)3-6-10/h2-7H2,1H3
InChIKey
LGGAZTKFNISBHK-UHFFFAOYSA-N
Computed Properties
Structural Parameters
Heavy atom count
13
Fraction Csp3
0.8
H-bond acceptors
2
Molar refractivity
48.21
TPSA
37.38
LogP / Solubility
WLOGP
1.12
MLOGP
0.98
XLogP3
-0.2
Consensus LogP
0.63
Log S (ESOL)
-1.67
Class (ESOL)
Soluble
Log S (Ali)
-1.86
Class (Ali)
Soluble
Log S (SILICOS-IT)
-1.77
Class (SILICOS-IT)
Soluble
ADME
GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-3.03
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
No
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
2.5
Customers Also Viewed
-
Teuvincene H
- CAS RN: 142299-73-8
- Product Code: starshine_CAS142299-73-8
- Purity/Analytical method: >99.0%
-
6-CHLORO-5-FLUOROBENZIMIDAZOLE-2-THIOL
- CAS RN: 142313-30-2
- Product Code: starshine_CAS142313-30-2
- Purity/Analytical method: >99.0%
-
2-[(1-METHYL-1H-IMIDAZOL-2-YL)THIO]ETHANAMINE
- CAS RN: 142313-55-1
- Product Code: SSC-053180
-
-
-
![CAS 142313-55-1 2-[(1-METHYL-1H-IMIDAZOL-2-YL)THIO]ETHANAMINE molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/142313-55-1.gif)
