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CAS 141764-85-4 2,4-Dichloro-5-(1,3-dioxolan-2-yl)thiazole molecular structure lightbox
CAS RN: 141764-85-4

2,4-Dichloro-5-(1,3-dioxolan-2-yl)thiazole

  • Product code: SSC-052430
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Historical Factory Record

Historical Supply Reference

This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.

  • Pack sizes on record: 1g
  • Available purity: ≥95%
  • Inventory rows with stock: 0
  • Bulk packaging: confirmed by inquiry
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Reference Pack Sizes

Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 141764-85-4
Pack Size Recorded Purity Available Qty Ship From Inquiry
1g ≥95% 0 Out of Stock Shenzhen Inquiry

141764-85-4 / 2,4-dichloro-5-(1,3-dioxolan-2-yl)-1,3-thiazole

Standard CAS: 141764-85-4 Multi CAS: No
Basic Information Computed Properties

Basic Information

CAS
141764-85-4
Multi CAS
No
Molecular Formula
C6H5Cl2NO2S
Molecular Weight
226.080000
Exact Mass
224.941805
SMILES
C1COC(O1)C2=C(N=C(S2)Cl)Cl
InChI
InChI=1S/C6H5Cl2NO2S/c7-4-3(12-6(8)9-4)5-10-1-2-11-5/h5H,1-2H2
InChIKey
PIXNOZYDMRHICD-UHFFFAOYSA-N

Computed Properties

Structural Parameters

Heavy atom count
12
Aromatic heavy atom count
5
Fraction Csp3
0.5
Rotatable bonds
1
H-bond acceptors
4
Molar refractivity
46.78
TPSA
31.35

LogP / Solubility

WLOGP
2.5
MLOGP
2.2
XLogP3
2.3
Consensus LogP
2.33
Log S (ESOL)
-3.06
Class (ESOL)
Poorly soluble
Log S (Ali)
-3.22
Class (Ali)
Poorly soluble
Log S (SILICOS-IT)
-3.32
Class (SILICOS-IT)
Poorly soluble

ADME

GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-2.33

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
1.5

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