[email protected]
CAS 1374639-74-3 Gemigliptin molecular structure lightbox
CAS RN: 1374639-74-3

Gemigliptin

Product Availability

Choose a grade to view its available package options.

9 package records9 with current stock2 grade groups
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20250114 100mg In stock Inquiry
Batchno.20260223 10mg In stock Inquiry
Batchno.20250917 50mg In stock Inquiry
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20260201 100mg In stock Shanghai Inquiry
Batchno.20250518 10mg In stock Shanghai Inquiry
Batchno.20260627 1g In stock Shanghai Inquiry
Batchno.20260604 250mg In stock Shanghai Inquiry
Batchno.20260401 50mg In stock Shanghai Inquiry
Batchno.20250704 5mg In stock Shanghai Inquiry
  • Product code: SSC-047017
GET A QUOTE
Historical Factory Record

Historical Supply Reference

This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.

  • Pack sizes on record: 1g
  • Available purity: ≥95%
  • Inventory rows with stock: 0
  • Bulk packaging: confirmed by inquiry
Request Bulk Quote

Reference Pack Sizes

Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 1374639-74-3
Pack Size Recorded Purity Available Qty Ship From Inquiry
1g ≥95% 0 Out of Stock Shenzhen Inquiry

1374639-74-3 / 1-[(2S)-2-amino-4-[2,4-bis(trifluoromethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-7-yl]-4-oxobutyl]-5,5-difluoropiperidin-2-one;(2R,3R)-2,3-dihydroxybutanedioic acid

Standard CAS: 1374639-74-3 Multi CAS: No
Basic Information Computed Properties

Basic Information

CAS
1374639-74-3
Multi CAS
No
Molecular Formula
C22H25F8N5O8
Molecular Weight
639.400000
Exact Mass
639.157538
SMILES
C1CC(CN(C1=O)C[C@H](CC(=O)N2CCC3=C(C2)N=C(N=C3C(F)(F)F)C(F)(F)F)N)(F)F.[C@@H]([C@H](C(=O)O)O)(C(=O)O)O
InChI
InChI=1S/C18H19F8N5O2.C4H6O6/c19-16(20)3-1-12(32)31(8-16)6-9(27)5-13(33)30-4-2-10-11(7-30)28-15(18(24,25)26)29-14(10)17(21,22)23;5-1(3(7)8)2(6)4(9)10/h9H,1-8,27H2;1-2,5-6H,(H,7,8)(H,9,10)/t9-;1-,2-/m01/s1
InChIKey
DPEZWSNXONTJHT-NDAAPVSOSA-N

Computed Properties

Structural Parameters

Heavy atom count
43
Aromatic heavy atom count
6
Fraction Csp3
0.64
Rotatable bonds
7
H-bond acceptors
9
H-bond donors
5
Molar refractivity
121.8
TPSA
207.48

LogP / Solubility

WLOGP
0.25
MLOGP
0.27
XLogP3
0.25
Consensus LogP
0.26
Log S (ESOL)
-3.6
Class (ESOL)
Poorly soluble
Log S (Ali)
-4.99
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-4.87
Class (SILICOS-IT)
Slightly soluble

ADME

GI absorption
Low
BBB permeant
No
P-gp substrate
Yes
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-6.44

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
No
Egan
No
Muegge
No
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
5.5

Customers Also Viewed

Get In Touch

Contact Us