[email protected]
CAS 137219-37-5 Plitidepsin molecular structure lightbox
CAS RN: 137219-37-5

Plitidepsin

Product Availability

Choose a grade to view its available package options.

4 package records4 with current stock1 grade group
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20260526 10mg In stock Shanghai Inquiry
Batchno.20251114 1mg In stock Shanghai Inquiry
Batchno.20260227 25mg In stock Shanghai Inquiry
Batchno.20250910 5mg In stock Shanghai Inquiry
  • Product code: starshine_CAS137219-37-5
  • Purity/Analytical Methods: >99.0%
GET A QUOTE

137219-37-5 / (2S)-N-[(2R)-1-[[(3S,6S,8S,12S,13R,16S,17R,20S,23S)-13-[(2S)-butan-2-yl]-12-hydroxy-20-[(4-methoxyphenyl)methyl]-6,17,21-trimethyl-3-(2-methylpropyl)-2,5,7,10,15,19,22-heptaoxo-8-propan-2-yl-9,18-dioxa-1,4,14,21-tetrazabicyclo[21.3.0]hexacosan-16-yl]amino]-4-methyl-1-oxopentan-2-yl]-N-methyl-1-(2-oxopropanoyl)pyrrolidine-2-carboxamide

Standard CAS: 137219-37-5 Multi CAS: No
Basic Information Computed Properties

Basic Information

CAS
137219-37-5
Multi CAS
No
Molecular Formula
C57H87N7O15
Molecular Weight
1110.300000
Exact Mass
1109.626015
SMILES
CC[C@H](C)[C@@H]1[C@H](CC(=O)O[C@H](C(=O)[C@@H](C(=O)N[C@H](C(=O)N2CCC[C@H]2C(=O)N([C@H](C(=O)O[C@@H]([C@@H](C(=O)N1)NC(=O)[C@@H](CC(C)C)N(C)C(=O)[C@@H]3CCCN3C(=O)C(=O)C)C)CC4=CC=C(C=C4)OC)C)CC(C)C)C)C(C)C)O
InChI
InChI=1S/C57H87N7O15/c1-15-33(8)46-44(66)29-45(67)79-49(32(6)7)48(68)34(9)50(69)58-39(26-30(2)3)54(73)64-25-17-19-41(64)56(75)62(13)43(28-37-20-22-38(77-14)23-21-37)57(76)78-36(11)47(52(71)59-46)60-51(70)42(27-31(4)5)61(12)55(74)40-18-16-24-63(40)53(72)35(10)65/h20-23,30-34,36,39-44,46-47,49,66H,15-19,24-29H2,1-14H3,(H,58,69)(H,59,71)(H,60,70)/t33-,34-,36+,39-,40-,41-,42+,43-,44-,46+,47-,49-/m0/s1
InChIKey
UUSZLLQJYRSZIS-LXNNNBEUSA-N

Computed Properties

Structural Parameters

Heavy atom count
79
Aromatic heavy atom count
6
Fraction Csp3
0.7
Rotatable bonds
15
H-bond acceptors
15
H-bond donors
4
Molar refractivity
289.19
TPSA
284.74

LogP / Solubility

WLOGP
2.52
MLOGP
2.33
XLogP3
5.7
Consensus LogP
3.52
Log S (ESOL)
-7.38
Class (ESOL)
Insoluble
Log S (Ali)
-10.49
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-10.77
Class (SILICOS-IT)
Insoluble

ADME

GI absorption
Low
BBB permeant
No
P-gp substrate
Yes
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-7.7

Drug-likeness / Medicinal Chemistry

Lipinski
No
Ghose
No
Veber
No
Egan
No
Muegge
No
Bioavailability score
0.17
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
10

Customers Also Viewed

Get In Touch

Contact Us