CAS RN: 1365888-06-7
GDC-0810(ARN-810)
Product Availability
Choose a grade to view its available package options.
11 package records4 with current stock4 grade groups
| Batch No. | Package | Availability | Warehouse | Lead Time | Inquiry |
|---|---|---|---|---|---|
| Batchno.20251222 | 1ml | In stock | Inquiry |
| Batch No. | Package | Availability | Warehouse | Lead Time | Inquiry |
|---|---|---|---|---|---|
| Batchno.20260211 | 100mg | Out of stock | Inquiry | ||
| Batchno.20260506 | 10mg | Out of stock | Inquiry | ||
| Batchno.20250314 | 1mg | In stock | Shanghai | Inquiry | |
| Batchno.20260508 | 25mg | Out of stock | Inquiry | ||
| Batchno.20250615 | 50mg | Out of stock | Inquiry | ||
| Batchno.20260628 | 5mg | In stock | Shanghai | Inquiry |
| Batch No. | Package | Availability | Warehouse | Lead Time | Inquiry |
|---|---|---|---|---|---|
| Batchno.20251003 | 5mg / 25mg | Out of stock | 5-7 business days | Inquiry |
- Product code: starshine_CAS1365888-06-7
- Purity/Analytical Methods: >99.0%
1365888-06-7 / (E)-3-[4-[(E)-2-(2-chloro-4-fluorophenyl)-1-(1H-indazol-5-yl)but-1-enyl]phenyl]prop-2-enoic acid
Basic Information
CAS
1365888-06-7
Multi CAS
No
Molecular Formula
C26H20ClFN2O2
Molecular Weight
446.900000
Exact Mass
446.119734
SMILES
CC/C(=C(/C1=CC=C(C=C1)/C=C/C(=O)O)\C2=CC3=C(C=C2)NN=C3)/C4=C(C=C(C=C4)F)Cl
InChI
InChI=1S/C26H20ClFN2O2/c1-2-21(22-10-9-20(28)14-23(22)27)26(18-8-11-24-19(13-18)15-29-30-24)17-6-3-16(4-7-17)5-12-25(31)32/h3-15H,2H2,1H3,(H,29,30)(H,31,32)/b12-5+,26-21+
InChIKey
BURHGPHDEVGCEZ-KJGLQBJMSA-N
Computed Properties
Structural Parameters
Heavy atom count
32
Aromatic heavy atom count
21
Fraction Csp3
0.08
Rotatable bonds
6
H-bond acceptors
2
H-bond donors
2
Molar refractivity
126.82
TPSA
65.98
LogP / Solubility
WLOGP
6.82
MLOGP
6.03
XLogP3
7.4
Consensus LogP
6.75
Log S (ESOL)
-7
Class (ESOL)
Insoluble
Log S (Ali)
-8.15
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-8.95
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
Low
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
No
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-0.6
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
No
Veber
Yes
Egan
No
Muegge
No
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
3
Customers Also Viewed
-
5-Ethynyl-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole
- CAS RN: 1365888-99-8
- Product Code: starshine_CAS1365888-99-8
- Purity/Analytical method: >99.0%
-
5-(But-1-yn-1-yl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole
- CAS RN: 1365889-00-4
- Product Code: starshine_CAS1365889-00-4
- Purity/Analytical method: >99.0%
-
5-broMo-3-fluoro-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole
- CAS RN: 1365889-96-8
- Product Code: starshine_CAS1365889-96-8
- Purity/Analytical method: >99.0%
-
PropanaMide, N-[2-(1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-ylidene)ethyl]-
- CAS RN: 1365920-11-1
- Product Code: starshine_CAS1365920-11-1
- Purity/Analytical method: >99.0%
-
N-[(3R)-Pyrrolidin-3-yl]pyridin-2-amine dihydrochloride
- CAS RN: 1365937-63-8
- Product Code: starshine_CAS1365937-63-8
- Purity/Analytical method: >99.0%
-
5-Ethoxy-1-methyl-1H-pyrazole-4-carboxylic acid
- CAS RN: 1365939-36-1
- Product Code: starshine_CAS1365939-36-1
- Purity/Analytical method: >99.0%
![CAS 1365920-11-1 PropanaMide, N-[2-(1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-ylidene)ethyl]- molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1365920-11-1.gif)
![CAS 1365937-63-8 N-[(3R)-Pyrrolidin-3-yl]pyridin-2-amine dihydrochloride molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/CB22698283(1).gif)
