CAS RN: 1338452-54-2
EveroliMus-d4
Product Availability
Choose a grade to view its available package options.
3 package records2 with current stock3 grade groups
| Batch No. | Package | Availability | Warehouse | Lead Time | Inquiry |
|---|---|---|---|---|---|
| Batchno.20250423 | 1mg | Confirm by inquiry | Inquiry |
| Batch No. | Package | Availability | Warehouse | Lead Time | Inquiry |
|---|---|---|---|---|---|
| Batchno.20251025 | 1mg | In stock | Shanghai | Inquiry |
| Batch No. | Package | Availability | Warehouse | Lead Time | Inquiry |
|---|---|---|---|---|---|
| Batchno.20250419 | 1mg | Out of stock | 5-7 business days | Inquiry |
- Product code: starshine_CAS1338452-54-2
- Purity/Analytical Methods: >99.0%
1338452-54-2 / (1R,9S,12S,15R,18R,19R,21R,23S,30S,32S,35R)-1,18-dihydroxy-19,30-dimethoxy-12-[(2R)-1-[(1S,3R,4R)-3-methoxy-4-(1,1,2,2-tetradeuterio-2-hydroxyethoxy)cyclohexyl]propan-2-yl]-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone
Basic Information
CAS
1338452-54-2
Multi CAS
No
Molecular Formula
C53H83NO14
Molecular Weight
962.200000
Exact Mass
961.606463
SMILES
[2H]C([2H])(C([2H])([2H])O[C@@H]1CC[C@H](C[C@H]1OC)C[C@@H](C)[C@@H]2CC(=O)[C@@H](C=C([C@H]([C@H](C(=O)[C@@H](C[C@@H](C=CC=CC=C([C@H](C[C@@H]3CC[C@H]([C@@](O3)(C(=O)C(=O)N4CCCC[C@H]4C(=O)O2)O)C)OC)C)C)C)OC)O)C)C)O
InChI
InChI=1S/C53H83NO14/c1-32-16-12-11-13-17-33(2)44(63-8)30-40-21-19-38(7)53(62,68-40)50(59)51(60)54-23-15-14-18-41(54)52(61)67-45(35(4)28-39-20-22-43(66-25-24-55)46(29-39)64-9)31-42(56)34(3)27-37(6)48(58)49(65-10)47(57)36(5)26-32/h11-13,16-17,27,32,34-36,38-41,43-46,48-49,55,58,62H,14-15,18-26,28-31H2,1-10H3/t32-,34-,35-,36-,38-,39+,40+,41+,43-,44+,45+,46-,48-,49+,53-/m1/s1/i24D2,25D2
InChIKey
HKVAMNSJSFKALM-FQJUTLEBSA-N
Computed Properties
Structural Parameters
Heavy atom count
68
Fraction Csp3
0.75
Rotatable bonds
9
H-bond acceptors
14
H-bond donors
3
Molar refractivity
255.96
TPSA
204.66
LogP / Solubility
WLOGP
6.2
MLOGP
5.54
XLogP3
5.9
Consensus LogP
5.88
Log S (ESOL)
-9.09
Class (ESOL)
Insoluble
Log S (Ali)
-11.89
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-12.11
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
Low
BBB permeant
No
P-gp substrate
Yes
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-4.17
Drug-likeness / Medicinal Chemistry
Lipinski
No
Ghose
No
Veber
No
Egan
No
Muegge
No
Bioavailability score
0.17
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
10
Safety & Transport
GHS Hazard Statements
H412 (100%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]
Precautionary Statement Codes
P273, and P501
Customers Also Viewed
-
![CAS 1338454-03-7 “(R)-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphole” molecular structure](data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%200%200'%3E%3C/svg%3E)
“(R)-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphole”
- CAS RN: 1338454-03-7
- Product Code: SSC-040875
-
(R)-3-(tert-butyl)-4-(2-methoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphole
- CAS RN: 1338454-28-6
- Product Code: SSC-040876
-
(R)-3-(tert-butyl)-4-(2,6-diisopropoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphole
- CAS RN: 1338454-38-8
- Product Code: SSC-040877
-
EPZ004777
- CAS RN: 1338466-77-5
- Product Code: starshine_CAS1338466-77-5
- Purity/Analytical method: >99.0%
-
tert-Butyl 4-(2-chloro-5-fluoropyrimidin-4-yl)piperazine-1-carboxylate
- CAS RN: 1338495-22-9
- Product Code: SSC-040881
-
OTS514
- CAS RN: 1338540-55-8
- Product Code: starshine_CAS1338540-55-8
- Purity/Analytical method: >99.0%
![CAS 1338454-03-7 “(R)-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphole” molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1338454-03-7.gif)
![CAS 1338454-28-6 (R)-3-(tert-butyl)-4-(2-methoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphole molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1338454-28-6.gif)
![CAS 1338454-38-8 (R)-3-(tert-butyl)-4-(2,6-diisopropoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphole molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1338454-38-8.gif)
