This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.
Dry Powder
Black shiny solid; [Merck Index] Black odorless powder; Insoluble in water
State
Solid
Computed Properties
Structural Parameters
Heavy atom count
5
Fraction Csp3
1
Molar refractivity
25.71
TPSA
0.0000
LogP / Solubility
WLOGP
-1.31
MLOGP
-1.17
XLogP3
-1.31
Consensus LogP
-1.26
Log S (ESOL)
0.64
Class (ESOL)
Highly soluble
Log S (Ali)
0.93
Class (Ali)
Highly soluble
Log S (SILICOS-IT)
1.07
Class (SILICOS-IT)
Highly soluble
ADME
GI absorption
Low
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-3.99
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
No
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
2.5
Safety & Transport
Pictogram(s)
Health Hazard
Signal
Danger
GHS Hazard Statements
H360 (19.5%): May damage fertility or the unborn child [Danger Reproductive toxicity]
H360FD (19.5%): May damage fertility; May damage the unborn child [Danger Reproductive toxicity]
Not Classified
Reported as not meeting GHS hazard criteria by 1 of 1 companies. For more detailed information, please visit ECHA C&L website.