CAS RN: 1185-53-1
Tris(hydroxymethyl)aminomethane Hydrochloride
Product Availability
Choose a grade to view its available package options.
8 package records8 with current stock4 grade groups
| Batch No. | Package | Availability | Warehouse | Lead Time | Inquiry |
|---|---|---|---|---|---|
| Batchno.20250306 | 5g / 25g / 100g / 500g | Confirm by inquiry | Shanghai | 8-10 business days | Inquiry |
| Batch No. | Package | Availability | Warehouse | Lead Time | Inquiry |
|---|---|---|---|---|---|
| Batchno.20260213 | 100g / 500g / 2.5kg / 12X500g | Confirm by inquiry | Shanghai, Shandong, Guangdong, Chongqing, Hebei | Inquiry |
| Batch No. | Package | Availability | Warehouse | Lead Time | Inquiry |
|---|---|---|---|---|---|
| Batchno.20260515 | 100g | In stock | Shanghai, Shandong | Inquiry | |
| Batchno.20251031 | 2.5kg | In stock | Shanghai, Shandong, Hebei | Inquiry | |
| Batchno.20250130 | 25g | In stock | Shanghai, Shandong, Chongqing, Hebei | Inquiry | |
| Batchno.20250921 | 500g | In stock | Shanghai, Shandong, Guangdong, Hebei | Inquiry |
- Product code: SSC-018297
Verified Factory Data
Supply Overview & Packaging Options
Packaging options, recorded purity, stock quantity and ship-from location below are generated from the current factory data table for this CAS.
- Pack sizes on record: 25g, 100g, 1000g, 500g, 1g
- Available purity: ≥97%, ＞97%
- Inventory rows with stock: 4
- Bulk packaging: confirmed by inquiry
Available Pack Sizes & Stock
Specific stock quantities are shown below. Price is not displayed online and is confirmed by inquiry.
| Pack Size | Recorded Purity | Available Qty | Ship From | Inquiry |
|---|---|---|---|---|
| 25g | ≥97% | 5 In Stock | Shenzhen | Inquiry |
| 100g | ≥97% | 5 In Stock | Shanghai | Inquiry |
| 1000g | ≥97% | 4 In Stock | Shenzhen | Inquiry |
| 500g | ≥97% | 3 In Stock | Shenzhen | Inquiry |
| 1g | ＞97% | 0 Out of Stock | Shanghai | Inquiry |
1185-53-1 / 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydrochloride
Tris hydrochloride | Tris(hydroxymethyl)aminomethane hydrochloride | 2-Amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride
Basic Information
CAS
1185-53-1
Multi CAS
Yes
Molecular Formula
C4H12ClNO3
Molecular Weight
157.590000
Exact Mass
157.050571
SMILES
C(C(CO)(CO)N)O.Cl
InChI
InChI=1S/C4H11NO3.ClH/c5-4(1-6,2-7)3-8;/h6-8H,1-3,5H2;1H
InChIKey
QKNYBSVHEMOAJP-UHFFFAOYSA-N
Synonyms
Tris hydrochloride
Tris(hydroxymethyl)aminomethane hydrochloride
2-Amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride
Tromethamine hydrochloride
TRIS HCl
Physical Properties
Physical Description
Other Solid
Hygroscopic solid
State
Solid
Computed Properties
Structural Parameters
Heavy atom count
9
Fraction Csp3
1
Rotatable bonds
3
H-bond acceptors
4
H-bond donors
4
Molar refractivity
35.42
TPSA
86.71
LogP / Solubility
WLOGP
-1.92
MLOGP
-1.69
XLogP3
-1.92
Consensus LogP
-1.84
Log S (ESOL)
0.59
Class (ESOL)
Highly soluble
Log S (Ali)
0.53
Class (Ali)
Highly soluble
Log S (SILICOS-IT)
0.55
Class (SILICOS-IT)
Highly soluble
ADME
GI absorption
Low
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-5.04
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
No
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
1.5
Safety & Transport
Pictogram(s)
Irritant
Signal
Warning
GHS Hazard Statements
H315 (42.2%): Causes skin irritation [Warning Skin corrosion/irritation]
H319 (42.2%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H335 (40.6%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Precautionary Statement Codes
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501
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![CAS 64431-96-5 1,3-Bis[tris(hydroxymethyl)methylamino]propane [for Buffer Material] molecular structure](https://starshinechemical.com/wp-content/uploads/2022/03/b1057-jpgcontextbwfzdgvyfhjvb3r8mzm0mzb8aw1hz2uvanblz3xoyzuvadlmlzg5mjg2mdy2mtc2mzavqjewntcuanbnfgixntk4nzhjndk3nde4zwu0oty4zte2ndkwndkynjgwnwjhyza5yzy2ogrin2yxy2rkzdywywnkmtjhodgwn2i.jpeg)
