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CAS 116-43-8 Succinylsulfathiazole molecular structure lightbox
CAS RN: 116-43-8

Succinylsulfathiazole

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5 package records5 with current stock2 grade groups
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20250816 100g In stock Inquiry
Batchno.20260127 250g In stock Inquiry
Batchno.20260605 25g In stock Inquiry
Batchno.20250926 5g In stock Inquiry
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20260407 1g / 5g / 25g / 100g / 250g Confirm by inquiry Shandong, Shanghai Inquiry
  • Product code: ICTS0581
  • Purity/Analytical Methods: >97.0%(T)(HPLC)
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116-43-8 / 4-oxo-4-[4-(1,3-thiazol-2-ylsulfamoyl)anilino]butanoic acid

succinylsulfathiazole | Colistatin | Sulfasuxidine

Standard CAS: 116-43-8 Multi CAS: Yes
Basic Information Computed Properties Safety & Transport

Basic Information

CAS
116-43-8
Multi CAS
Yes
Molecular Formula
C13H13N3O5S2
Molecular Weight
355.400000
Exact Mass
355.029663
SMILES
C1=CC(=CC=C1NC(=O)CCC(=O)O)S(=O)(=O)NC2=NC=CS2
InChI
InChI=1S/C13H13N3O5S2/c17-11(5-6-12(18)19)15-9-1-3-10(4-2-9)23(20,21)16-13-14-7-8-22-13/h1-4,7-8H,5-6H2,(H,14,16)(H,15,17)(H,18,19)
InChIKey
SKVLYVHULOWXTD-UHFFFAOYSA-N
Synonyms
succinylsulfathiazole Colistatin Sulfasuxidine Cremosuxidine Sulfadigesin

Computed Properties

Structural Parameters

Heavy atom count
23
Aromatic heavy atom count
11
Fraction Csp3
0.15
Rotatable bonds
7
H-bond acceptors
6
H-bond donors
3
Molar refractivity
84.86
TPSA
125.46

LogP / Solubility

WLOGP
1.75
MLOGP
1.56
XLogP3
-0.7
Consensus LogP
0.87
Log S (ESOL)
-3.04
Class (ESOL)
Poorly soluble
Log S (Ali)
-3.74
Class (Ali)
Poorly soluble
Log S (SILICOS-IT)
-4.26
Class (SILICOS-IT)
Slightly soluble

ADME

GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-3.65

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
2.5

Safety & Transport

Pictogram(s)
Irritant
Signal
Warning
GHS Hazard Statements
H317 (97.6%): May cause an allergic skin reaction [Warning Sensitization, Skin]
Precautionary Statement Codes
P261, P272, P280, P302+P352, P321, P333+P317, P362+P364, and P501

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