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CAS 1131335-72-2 6-Bromo-2-(trimethylsilyl)furo[3,2-b]pyridine molecular structure lightbox
CAS RN: 1131335-72-2

6-Bromo-2-(trimethylsilyl)furo[3,2-b]pyridine

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1 package records0 with current stock1 grade group
Batch No.PackageAvailabilityLead TimeInquiry
Batchno.20250118 100mg Out of stock 15 business days Inquiry
  • Product code: starshine_CAS1131335-72-2
  • Purity/Analytical Methods: >99.0%
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1131335-72-2 / (6-bromofuro[3,2-b]pyridin-2-yl)-trimethylsilane

6-Bromo-2-(trimethylsilyl)furo[3,2-b]pyridine | C10H12BrNOSi | (6-bromofuro[3,2-b]pyridin-2-yl)-trimethylsilane

Standard CAS: 1131335-72-2 Multi CAS: No
Basic Information Computed Properties

Basic Information

CAS
1131335-72-2
Multi CAS
No
Molecular Formula
C10H12BrNOSi
Molecular Weight
270.200000
Exact Mass
268.987150
SMILES
C[Si](C)(C)C1=CC2=C(O1)C=C(C=N2)Br
InChI
InChI=1S/C10H12BrNOSi/c1-14(2,3)10-5-8-9(13-10)4-7(11)6-12-8/h4-6H,1-3H3
InChIKey
IXYOZGPZWPDQKP-UHFFFAOYSA-N
Synonyms
6-Bromo-2-(trimethylsilyl)furo[3,2-b]pyridine C10H12BrNOSi (6-bromofuro[3,2-b]pyridin-2-yl)-trimethylsilane MFCD11857748 SCHEMBL4821101

Computed Properties

Structural Parameters

Heavy atom count
14
Aromatic heavy atom count
9
Fraction Csp3
0.3
Rotatable bonds
1
H-bond acceptors
2
Molar refractivity
64.69
TPSA
26.03

LogP / Solubility

WLOGP
3.14
MLOGP
2.77
XLogP3
3.14
Consensus LogP
3.02
Log S (ESOL)
-3.9
Class (ESOL)
Poorly soluble
Log S (Ali)
-4.04
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-4.14
Class (SILICOS-IT)
Slightly soluble

ADME

GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-2.14

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
Yes
Synthetic Accessibility
1.5

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