[email protected]
CAS 1130115-44-4 Sorafenib-d3 molecular structure lightbox
CAS RN: 1130115-44-4

Sorafenib-d3

Product Availability

Choose a grade to view its available package options.

10 package records9 with current stock3 grade groups
Batch No.PackageAvailabilityWarehouseLead TimeInquiry
Batchno.20250401 100mg In stock Shanghai, Shenzhen Inquiry
Batchno.20250615 250mg In stock Shanghai, Wuhan Inquiry
Batchno.20260404 50mg In stock Shanghai, Shenzhen Inquiry
Batch No.PackageAvailabilityWarehouseLead TimeInquiry
Batchno.20250610 5mg / 10mg / 25mg / 100mg Out of stock 5-7 business days Inquiry
Batch No.PackageAvailabilityWarehouseLead TimeInquiry
Batchno.20250820 100mg In stock Inquiry
Batchno.20260623 10mg In stock Inquiry
Batchno.20250725 200mg In stock Inquiry
Batchno.20260616 25mg In stock Inquiry
Batchno.20250425 50mg In stock Inquiry
Batchno.20260411 5mg In stock Inquiry
  • Product code: SSC-013240
GET A QUOTE
Historical Factory Record

Historical Supply Reference

This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.

  • Pack sizes on record: 0.25g
  • Available purity: ≥95%
  • Inventory rows with stock: 0
  • Bulk packaging: confirmed by inquiry
Request Bulk Quote

Reference Pack Sizes

Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 1130115-44-4
Pack Size Recorded Purity Available Qty Ship From Inquiry
0.25g ≥95% 0 Out of Stock Hong Kong Inquiry

1130115-44-4 / 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-(trideuteriomethyl)pyridine-2-carboxamide

Sorafenib | BAY 43-9006 | sorafenibum

Standard CAS: 1130115-44-4 Multi CAS: Yes
Basic Information Computed Properties

Basic Information

CAS
1130115-44-4
Multi CAS
Yes
Molecular Formula
C21H16ClF3N4O3
Molecular Weight
467.800000
Exact Mass
467.105133
SMILES
[2H]C([2H])([2H])NC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F
InChI
InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)/i1D3
InChIKey
MLDQJTXFUGDVEO-FIBGUPNXSA-N
Synonyms
Sorafenib BAY 43-9006 sorafenibum 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide

Computed Properties

Structural Parameters

Heavy atom count
32
Aromatic heavy atom count
18
Fraction Csp3
0.1
Rotatable bonds
5
H-bond acceptors
4
H-bond donors
3
Molar refractivity
113.24
TPSA
92.35

LogP / Solubility

WLOGP
5.55
MLOGP
4.92
XLogP3
4.1
Consensus LogP
4.86
Log S (ESOL)
-6.3
Class (ESOL)
Insoluble
Log S (Ali)
-7.38
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-7.89
Class (SILICOS-IT)
Insoluble

ADME

GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-1.62

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
No
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
2.5

Customers Also Viewed

Get In Touch

Contact Us