![CAS 1124381-43-6 N-(5-(cyclopropylamino)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)nicotinamide molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1124381-43-6.gif)
CAS RN: 1124381-43-6
N-(5-(cyclopropylamino)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)nicotinamide
Product Availability
Choose a grade to view its available package options.
6 package records0 with current stock2 grade groups
| Batch No. | Package | Availability | Lead Time | Inquiry |
|---|---|---|---|---|
| Batchno.20260223 | 1mg | Out of stock | 5-7 business days | Inquiry |
- Product code: starshine_CAS1124381-43-6
- Purity/Analytical Methods: >99.0%
1124381-43-6 / N-[5-(cyclopropylamino)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]pyridine-3-carboxamide
MSC2032964A | MSC-2032964A | U7AP46TK3Q
Basic Information
CAS
1124381-43-6
Multi CAS
No
Molecular Formula
C16H13F3N6O
Molecular Weight
362.310000
Exact Mass
362.110294
SMILES
C1CC1NC2=CC(=CC3=NC(=NN23)NC(=O)C4=CN=CC=C4)C(F)(F)F
InChI
InChI=1S/C16H13F3N6O/c17-16(18,19)10-6-12(21-11-3-4-11)25-13(7-10)22-15(24-25)23-14(26)9-2-1-5-20-8-9/h1-2,5-8,11,21H,3-4H2,(H,23,24,26)
InChIKey
XUKGFHHTSUKORV-UHFFFAOYSA-N
Synonyms
MSC2032964A
MSC-2032964A
U7AP46TK3Q
3-Pyridinecarboxamide, N-(5-(cyclopropylamino)-7-(trifluoromethyl)(1,2,4)triazolo(1,5-a)pyridin-2-yl)-
RefChem:159937
Computed Properties
Structural Parameters
Heavy atom count
26
Aromatic heavy atom count
15
Fraction Csp3
0.25
Rotatable bonds
4
H-bond acceptors
6
H-bond donors
2
Molar refractivity
86.82
TPSA
84.21
LogP / Solubility
WLOGP
2.97
MLOGP
2.63
XLogP3
2.6
Consensus LogP
2.73
Log S (ESOL)
-4.12
Class (ESOL)
Slightly soluble
Log S (Ali)
-4.68
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-4.96
Class (SILICOS-IT)
Slightly soluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-2.82
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
3
Customers Also Viewed
-
S-99
- CAS RN: 1124381-69-6
- Product Code: starshine_CAS1124381-69-6
- Purity/Analytical method: >99.0%
-
6-BroMo-5-Methyl-[1,2,4]triazolo[1,5-a]pyridin-2-aMine
- CAS RN: 1124382-65-5
- Product Code: SSC-012870
-
8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine
- CAS RN: 1124382-72-4
- Product Code: SSC-012871
-
ethyl {[(5-bromo-6-methylpyridin-2-yl)amino]carbonothioyl}carbamate
- CAS RN: 1124382-96-2
- Product Code: SSC-012872
-
ethyl {[(3-broMopyridin-2-yl)aMino]carbonothioyl}carbaMate
- CAS RN: 1124383-00-1
- Product Code: SSC-012873
-
5,7-Dichloro-[1,2,4]triazolo[1,5-a]pyridin-2-aMine
- CAS RN: 1124383-04-5
- Product Code: SSC-012874
![CAS 1124382-65-5 6-BroMo-5-Methyl-[1,2,4]triazolo[1,5-a]pyridin-2-aMine molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1124382-65-5.gif)
![CAS 1124382-72-4 8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1124382-72-4.gif)
![CAS 1124382-96-2 ethyl {[(5-bromo-6-methylpyridin-2-yl)amino]carbonothioyl}carbamate molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1124382-96-2.gif)
![CAS 1124383-00-1 ethyl {[(3-broMopyridin-2-yl)aMino]carbonothioyl}carbaMate molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1124383-00-1.gif)
![CAS 1124383-04-5 5,7-Dichloro-[1,2,4]triazolo[1,5-a]pyridin-2-aMine molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1124383-04-5.gif)