CAS RN: 109351-34-0

(R)-Terazosin

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6 package records3 with current stock1 grade group
Batch No.PackageAvailabilityWarehouseLead TimeInquiry
Batchno.20251213 100mg Out of stock Inquiry
Batchno.20250320 10mg In stock Shanghai Inquiry
Batchno.20250926 250mg Out of stock Inquiry
Batchno.20251120 25mg In stock Shanghai Inquiry
Batchno.20251129 50mg In stock Shanghai Inquiry
Batchno.20250822 5mg / 10mg Out of stock 5-7 business days Inquiry
  • Product code: starshine_CAS109351-34-0
  • Purity/Analytical Methods: >99.0%
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109351-34-0 / [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-[(2R)-oxolan-2-yl]methanone

terazosin | Terazosine | Fosfomic

Standard CAS: 109351-34-0 Multi CAS: Yes

Basic Information

CAS
109351-34-0
Multi CAS
Yes
Molecular Formula
C19H25N5O4
Molecular Weight
387.400000
Exact Mass
387.190654
SMILES
COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)[C@H]4CCCO4)N)OC
InChI
InChI=1S/C19H25N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h10-11,14H,3-9H2,1-2H3,(H2,20,21,22)/t14-/m1/s1
InChIKey
VCKUSRYTPJJLNI-CQSZACIVSA-N
Synonyms
terazosin Terazosine Fosfomic Terazosina Blavin

Computed Properties

Structural Parameters

Heavy atom count
28
Aromatic heavy atom count
10
Fraction Csp3
0.53
Rotatable bonds
4
H-bond acceptors
8
H-bond donors
1
Molar refractivity
104.82
TPSA
103.04

LogP / Solubility

WLOGP
1.06
MLOGP
0.95
XLogP3
1.4
Consensus LogP
1.14
Log S (ESOL)
-2.91
Class (ESOL)
Moderately soluble
Log S (Ali)
-3.5
Class (Ali)
Poorly soluble
Log S (SILICOS-IT)
-3.54
Class (SILICOS-IT)
Poorly soluble

ADME

GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-4.33

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
3.5

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