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CAS 1086398-43-7 2-CHLORO-6-FLUORO-8-METHOXYQUINOLINE molecular structure lightbox
CAS RN: 1086398-43-7

2-CHLORO-6-FLUORO-8-METHOXYQUINOLINE

Product Availability

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1 package records0 with current stock1 grade group
Batch No.PackageAvailabilityLead TimeInquiry
Batchno.20250909 100mg / 1g Out of stock 5-7 business days Inquiry
  • Product code: SSC-009951
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Historical Factory Record

Historical Supply Reference

This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.

  • Pack sizes on record: 0.25g
  • Available purity: ＞97%
  • Inventory rows with stock: 0
  • Bulk packaging: confirmed by inquiry
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Reference Pack Sizes

Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 1086398-43-7
Pack Size Recorded Purity Available Qty Ship From Inquiry
0.25g ＞97% 0 Out of Stock Beijing Inquiry

1086398-43-7 / 2-chloro-6-fluoro-8-methoxyquinoline

2-Chloro-6-fluoro-8-methoxyquinoline | MFCD11501269 | 2-Chloro-6-fluoro-8-methoxy-quinoline

Standard CAS: 1086398-43-7 Multi CAS: No
Basic Information Computed Properties

Basic Information

CAS
1086398-43-7
Multi CAS
No
Molecular Formula
C10H7ClFNO
Molecular Weight
211.620000
Exact Mass
211.020020
SMILES
COC1=C2C(=CC(=C1)F)C=CC(=N2)Cl
InChI
InChI=1S/C10H7ClFNO/c1-14-8-5-7(12)4-6-2-3-9(11)13-10(6)8/h2-5H,1H3
InChIKey
CUJLXWMQSIFPSQ-UHFFFAOYSA-N
Synonyms
2-Chloro-6-fluoro-8-methoxyquinoline MFCD11501269 2-Chloro-6-fluoro-8-methoxy-quinoline AKOS013527988 SB69367

Computed Properties

Structural Parameters

Heavy atom count
14
Aromatic heavy atom count
10
Fraction Csp3
0.1
Rotatable bonds
1
H-bond acceptors
2
Molar refractivity
53.26
TPSA
22.12

LogP / Solubility

WLOGP
3.04
MLOGP
2.67
XLogP3
3.2
Consensus LogP
2.97
Log S (ESOL)
-3.53
Class (ESOL)
Poorly soluble
Log S (Ali)
-3.49
Class (Ali)
Poorly soluble
Log S (SILICOS-IT)
-3.68
Class (SILICOS-IT)
Poorly soluble

ADME

GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-1.86

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
1.5

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