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CAS 108481-92-1 2-Amino-4-(4-isopropylphenyl)- thiazole molecular structure lightbox
CAS RN: 108481-92-1

2-Amino-4-(4-isopropylphenyl)- thiazole

  • Product code: SSC-009780
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Verified Factory Data

Supply Overview & Packaging Options

Packaging options, recorded purity, stock quantity and ship-from location below are generated from the current factory data table for this CAS.

  • Pack sizes on record: 1g, 5g, 0.1g, 0.25g, 10g
  • Available purity: >97%
  • Inventory rows with stock: 8
  • Bulk packaging: confirmed by inquiry
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Available Pack Sizes & Stock

Specific stock quantities are shown below. Price is not displayed online and is confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 108481-92-1
Pack Size Recorded Purity Available Qty Ship From Inquiry
1g -- 5 In Stock Beijing Inquiry
1g >97% 5 In Stock Hong Kong Inquiry
5g -- 3 In Stock Beijing Inquiry
5g >97% 3 In Stock Beijing Inquiry
0.1g -- 1 In Stock Shenzhen Inquiry
0.1g >97% 1 In Stock Hong Kong Inquiry
0.25g -- 1 In Stock Shanghai Inquiry
0.25g >97% 1 In Stock Hong Kong Inquiry
10g -- 0 Out of Stock Shenzhen Inquiry
10g >97% 0 Out of Stock Shanghai Inquiry

108481-92-1 / 4-(4-propan-2-ylphenyl)-1,3-thiazol-2-amine

4-(4-Isopropyl-phenyl)-thiazol-2-ylamine | DTXSID30350101 | RefChem:288067

Standard CAS: 108481-92-1 Multi CAS: Yes
Basic Information Computed Properties Safety & Transport

Basic Information

CAS
108481-92-1
Multi CAS
Yes
Molecular Formula
C12H14N2S
Molecular Weight
218.320000
Exact Mass
218.087770
SMILES
CC(C)C1=CC=C(C=C1)C2=CSC(=N2)N
InChI
InChI=1S/C12H14N2S/c1-8(2)9-3-5-10(6-4-9)11-7-15-12(13)14-11/h3-8H,1-2H3,(H2,13,14)
InChIKey
UFBAQAAATDLTAZ-UHFFFAOYSA-N
Synonyms
4-(4-Isopropyl-phenyl)-thiazol-2-ylamine DTXSID30350101 RefChem:288067 DTXCID10301171 2-amino-4-(4-isopropylphenyl)thiazole

Computed Properties

Structural Parameters

Heavy atom count
15
Aromatic heavy atom count
11
Fraction Csp3
0.25
Rotatable bonds
2
H-bond acceptors
3
H-bond donors
1
Molar refractivity
66.05
TPSA
38.91

LogP / Solubility

WLOGP
3.52
MLOGP
3.1
XLogP3
3.4
Consensus LogP
3.34
Log S (ESOL)
-3.82
Class (ESOL)
Poorly soluble
Log S (Ali)
-3.89
Class (Ali)
Poorly soluble
Log S (SILICOS-IT)
-4.24
Class (SILICOS-IT)
Slightly soluble

ADME

GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-1.56

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
1.5

Safety & Transport

Pictogram(s)
Acute Toxic Irritant
Signal
Danger
GHS Hazard Statements
H301 (33.3%): Toxic if swallowed [Danger Acute toxicity, oral] H302 (66.7%): Harmful if swallowed [Warning Acute toxicity, oral] H312 (33.3%): Harmful in contact with skin [Warning Acute toxicity, dermal] H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
Precautionary Statement Codes
P261, P264, P264+P265, P270, P271, P280, P301+P316, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

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