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CAS 1071540-51-6 7-Chloro-2-(triMethylsilyl)furo[3,2-b]pyridine molecular structure lightbox
CAS RN: 1071540-51-6

7-Chloro-2-(triMethylsilyl)furo[3,2-b]pyridine

  • Product code: SSC-008611
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Historical Factory Record

Historical Supply Reference

This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.

  • Pack sizes on record: 0.25g, 1g
  • Available purity: >95%
  • Inventory rows with stock: 0
  • Bulk packaging: confirmed by inquiry
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Reference Pack Sizes

Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 1071540-51-6
Pack Size Recorded Purity Available Qty Ship From Inquiry
0.25g >95% 0 Out of Stock Beijing Inquiry
1g >95% 0 Out of Stock Shenzhen Inquiry

1071540-51-6 / (7-chlorofuro[3,2-b]pyridin-2-yl)-trimethylsilane

7-Chloro-2-(trimethylsilyl)furo[3,2-b]pyridine | (7-chlorofuro[3,2-b]pyridin-2-yl)-trimethylsilane | C10H12ClNOSi

Standard CAS: 1071540-51-6 Multi CAS: Yes
Basic Information Computed Properties

Basic Information

CAS
1071540-51-6
Multi CAS
Yes
Molecular Formula
C10H12ClNOSi
Molecular Weight
225.740000
Exact Mass
225.037668
SMILES
C[Si](C)(C)C1=CC2=NC=CC(=C2O1)Cl
InChI
InChI=1S/C10H12ClNOSi/c1-14(2,3)9-6-8-10(13-9)7(11)4-5-12-8/h4-6H,1-3H3
InChIKey
AYTYKFMMCYBPDB-UHFFFAOYSA-N
Synonyms
7-Chloro-2-(trimethylsilyl)furo[3,2-b]pyridine (7-chlorofuro[3,2-b]pyridin-2-yl)-trimethylsilane C10H12ClNOSi MFCD24387170 7-Chloro-2-(trimethylsilyl)furo(3,2-b)pyridine

Computed Properties

Structural Parameters

Heavy atom count
14
Aromatic heavy atom count
9
Fraction Csp3
0.3
Rotatable bonds
1
H-bond acceptors
2
Molar refractivity
62
TPSA
26.03

LogP / Solubility

WLOGP
3.03
MLOGP
2.67
XLogP3
3.03
Consensus LogP
2.91
Log S (ESOL)
-3.56
Class (ESOL)
Poorly soluble
Log S (Ali)
-3.6
Class (Ali)
Poorly soluble
Log S (SILICOS-IT)
-3.76
Class (SILICOS-IT)
Poorly soluble

ADME

GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-1.95

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
1.5

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