[email protected]
CAS 1065092-35-4 8-bromo-5-fluoroquinolin-4-ol molecular structure lightbox
CAS RN: 1065092-35-4

8-bromo-5-fluoroquinolin-4-ol

Product Availability

Choose a grade to view its available package options.

1 package records0 with current stock1 grade group
Batch No.PackageAvailabilityLead TimeInquiry
Batchno.20250518 100mg / 250mg / 1g Out of stock 8-10 business days Inquiry
  • Product code: starshine_CAS1065092-35-4
  • Purity/Analytical Methods: >99.0%
GET A QUOTE

1065092-35-4 / 8-bromo-5-fluoro-1H-quinolin-4-one

8-BROMO-5-FLUOROQUINOLIN-4-OL | 8-Bromo-5-fluoro-1H-quinolin-4-one | 8-Bromo-5-fluoroquinolin-4(1H)-one

Standard CAS: 1065092-35-4 Multi CAS: No
Basic Information Computed Properties

Basic Information

CAS
1065092-35-4
Multi CAS
No
Molecular Formula
C9H5BrFNO
Molecular Weight
242.040000
Exact Mass
240.953850
SMILES
C1=CC(=C2C(=C1F)C(=O)C=CN2)Br
InChI
InChI=1S/C9H5BrFNO/c10-5-1-2-6(11)8-7(13)3-4-12-9(5)8/h1-4H,(H,12,13)
InChIKey
NGLVFYGOSNNWEE-UHFFFAOYSA-N
Synonyms
8-BROMO-5-FLUOROQUINOLIN-4-OL 8-Bromo-5-fluoro-1H-quinolin-4-one 8-Bromo-5-fluoroquinolin-4(1H)-one MFCD15527288 SCHEMBL27238854

Computed Properties

Structural Parameters

Heavy atom count
13
Aromatic heavy atom count
10
H-bond acceptors
1
H-bond donors
1
Molar refractivity
52.23
TPSA
32.86

LogP / Solubility

WLOGP
2.43
MLOGP
2.14
XLogP3
2.3
Consensus LogP
2.29
Log S (ESOL)
-3.44
Class (ESOL)
Poorly soluble
Log S (Ali)
-3.3
Class (Ali)
Poorly soluble
Log S (SILICOS-IT)
-3.25
Class (SILICOS-IT)
Poorly soluble

ADME

GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-2.47

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
1.5

Customers Also Viewed

Get In Touch

Contact Us