CAS RN: 106392-12-5

Poloxamer 188 CRS

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6 package records6 with current stock1 grade group
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20260503 100g In stock Shanghai, Shandong, Guangdong, Chongqing Inquiry
Batchno.20260414 1g In stock Shanghai, Shandong, Chongqing, Hebei Inquiry
Batchno.20250816 2.5kg In stock Shandong Inquiry
Batchno.20250421 25g In stock Shanghai, Shandong, Guangdong, Chongqing, Hebei Inquiry
Batchno.20250117 500g In stock Shanghai, Shandong, Guangdong Inquiry
Batchno.20260215 5g In stock Shanghai, Guangdong, Chongqing Inquiry
  • Product code: starshine_CAS106392-12-5
  • Purity/Analytical Methods: >99.0%
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106392-12-5 / 2-methyloxirane;oxirane

CRL-8131 | RefChem:1082259 | 2-methyloxirane;oxirane

Standard CAS: 106392-12-5 Multi CAS: Yes

Basic Information

CAS
106392-12-5
Multi CAS
Yes
Molecular Formula
C5H10O2
Molecular Weight
102.130000
Exact Mass
102.068080
SMILES
CC1CO1.C1CO1
InChI
InChI=1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2
InChIKey
RVGRUAULSDPKGF-UHFFFAOYSA-N
Synonyms
CRL-8131 RefChem:1082259 2-methyloxirane;oxirane TERGITOL(TM)XH(NONIONIC) Pluronic F-68

Computed Properties

Structural Parameters

Heavy atom count
7
Fraction Csp3
1
H-bond acceptors
2
Molar refractivity
26.23
TPSA
25.06

LogP / Solubility

WLOGP
0.42
MLOGP
0.36
XLogP3
0.42
Consensus LogP
0.4
Log S (ESOL)
-0.74
Class (ESOL)
Very soluble
Log S (Ali)
-0.7
Class (Ali)
Very soluble
Log S (SILICOS-IT)
-0.67
Class (SILICOS-IT)
Very soluble

ADME

GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-3.04

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
No
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
2

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