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CAS 1058137-23-7 E-3810 molecular structure lightbox
CAS RN: 1058137-23-7

E-3810

Product Availability

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15 package records14 with current stock4 grade groups
Batch No.PackageAvailabilityWarehouseLead TimeInquiry
Batchno.20260302 2mg / 5mg Out of stock 8-10 business days Inquiry
Batch No.PackageAvailabilityWarehouseLead TimeInquiry
Batchno.20251010 100mg In stock Shanghai Inquiry
Batchno.20250602 10mg In stock Shanghai Inquiry
Batchno.20251201 1mg In stock Shanghai Inquiry
Batchno.20251002 250mg In stock Shanghai Inquiry
Batchno.20260308 25mg In stock Shanghai Inquiry
Batchno.20250404 50mg In stock Shanghai Inquiry
Batchno.20260324 5mg In stock Shanghai Inquiry
Batch No.PackageAvailabilityWarehouseLead TimeInquiry
Batchno.20250707 100mg In stock Inquiry
Batchno.20250905 10mg In stock Inquiry
Batchno.20250826 1mg In stock Inquiry
Batchno.20251020 25mg In stock Inquiry
Batchno.20260627 50mg In stock Inquiry
Batchno.20260502 5mg In stock Inquiry
Batch No.PackageAvailabilityWarehouseLead TimeInquiry
Batchno.20251209 1ml In stock Inquiry
  • Product code: SSC-007512
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Historical Factory Record

Historical Supply Reference

This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.

  • Pack sizes on record: 0.25g
  • Available purity: ≥95%
  • Inventory rows with stock: 0
  • Bulk packaging: confirmed by inquiry
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Reference Pack Sizes

Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 1058137-23-7
Pack Size Recorded Purity Available Qty Ship From Inquiry
0.25g ≥95% 0 Out of Stock Beijing Inquiry

1058137-23-7 / 6-[7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl]oxy-N-methylnaphthalene-1-carboxamide

Lucitanib | E-3810 | E-3810 amine

Standard CAS: 1058137-23-7 Multi CAS: Yes
Basic Information Computed Properties

Basic Information

CAS
1058137-23-7
Multi CAS
Yes
Molecular Formula
C26H25N3O4
Molecular Weight
443.500000
Exact Mass
443.184506
SMILES
CNC(=O)C1=CC=CC2=C1C=CC(=C2)OC3=C4C=C(C(=CC4=NC=C3)OCC5(CC5)N)OC
InChI
InChI=1S/C26H25N3O4/c1-28-25(30)19-5-3-4-16-12-17(6-7-18(16)19)33-22-8-11-29-21-14-24(23(31-2)13-20(21)22)32-15-26(27)9-10-26/h3-8,11-14H,9-10,15,27H2,1-2H3,(H,28,30)
InChIKey
CUDVHEFYRIWYQD-UHFFFAOYSA-N
Synonyms
Lucitanib E-3810 E-3810 amine PP449XA4BH AL-3810

Computed Properties

Structural Parameters

Heavy atom count
33
Aromatic heavy atom count
20
Fraction Csp3
0.23
Rotatable bonds
7
H-bond acceptors
6
H-bond donors
2
Molar refractivity
127.35
TPSA
95.7

LogP / Solubility

WLOGP
4.42
MLOGP
3.92
XLogP3
3.6
Consensus LogP
3.98
Log S (ESOL)
-5.36
Class (ESOL)
Slightly soluble
Log S (Ali)
-6.39
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-7.05
Class (SILICOS-IT)
Insoluble

ADME

GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-2.29

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
3.5

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