![CAS 105628-72-6 1-[(1,2-DIHYDRO-1-OXO-5-ISOQUINOLINYL)SULFONYL]HEXAHYDRO-1H-1,4-DIAZEPINE molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/105628-72-6.gif)
CAS RN: 105628-72-6
1-[(1,2-DIHYDRO-1-OXO-5-ISOQUINOLINYL)SULFONYL]HEXAHYDRO-1H-1,4-DIAZEPINE
Product Availability
Choose a grade to view its available package options.
11 package records9 with current stock2 grade groups
| Batch No. | Package | Availability | Warehouse | Lead Time | Inquiry |
|---|---|---|---|---|---|
| Batchno.20250413 | 100mg | In stock | Shanghai, Shenzhen | Inquiry | |
| Batchno.20251209 | 10mg | In stock | Shanghai | Inquiry | |
| Batchno.20260624 | 1mg | In stock | Shanghai | Inquiry | |
| Batchno.20250601 | 250mg | Out of stock | Inquiry | ||
| Batchno.20250226 | 25mg | In stock | Shanghai, Wuhan | Inquiry | |
| Batchno.20251014 | 50mg | In stock | Shanghai, Wuhan | Inquiry | |
| Batchno.20250418 | 5mg | In stock | Shanghai | Inquiry |
- Product code: SSC-007346
Historical Factory Record
Historical Supply Reference
This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.
- Pack sizes on record: 0.25g
- Available purity: ≥95%
- Inventory rows with stock: 0
- Bulk packaging: confirmed by inquiry
Reference Pack Sizes
Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.
| Pack Size | Recorded Purity | Available Qty | Ship From | Inquiry |
|---|---|---|---|---|
| 0.25g | ≥95% | 0 Out of Stock | Beijing | Inquiry |
105628-72-6 / 5-(1,4-diazepan-1-ylsulfonyl)-2H-isoquinolin-1-one
HYDROXYFASUDIL | Hydroxy-Fasudil | HA-1100
Basic Information
CAS
105628-72-6
Multi CAS
Yes
Molecular Formula
C14H17N3O3S
Molecular Weight
307.370000
Exact Mass
307.099063
SMILES
C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CNC3=O
InChI
InChI=1S/C14H17N3O3S/c18-14-12-3-1-4-13(11(12)5-7-16-14)21(19,20)17-9-2-6-15-8-10-17/h1,3-5,7,15H,2,6,8-10H2,(H,16,18)
InChIKey
ZAVGJDAFCZAWSZ-UHFFFAOYSA-N
Synonyms
HYDROXYFASUDIL
Hydroxy-Fasudil
HA-1100
EYH4AU7P63
RefChem:789488
Computed Properties
Structural Parameters
Heavy atom count
21
Aromatic heavy atom count
10
Fraction Csp3
0.36
Rotatable bonds
2
H-bond acceptors
4
H-bond donors
2
Molar refractivity
80.81
TPSA
82.27
LogP / Solubility
WLOGP
0.51
MLOGP
0.46
XLogP3
0.2
Consensus LogP
0.39
Log S (ESOL)
-2.29
Class (ESOL)
Moderately soluble
Log S (Ali)
-2.45
Class (Ali)
Moderately soluble
Log S (SILICOS-IT)
-2.32
Class (SILICOS-IT)
Moderately soluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-4.23
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
Yes
Synthetic Accessibility
2.5
Customers Also Viewed
-
-
-
-
-
2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE
- CAS RN: 105650-23-5
- Product Code: SSC-007368
-
![CAS 105650-23-5 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/105650-23-5.gif)
