![CAS 105384-38-1 N,O-Bis(diethylhydrogensilyl)trifluoroacetamide [Simultaneous cyclic silylene and silyl derivatizing reagent for GC] molecular structure](https://starshinechemical.com/wp-content/uploads/2022/03/b1435-jpgcontextbwfzdgvyfhjvb3r8mzazmjf8aw1hz2uvanblz3xoyzavadlilzg5mjg2nji3ode5odivqje0mzuuanbnfdezztlingvhodyznzdindlhnwq1yjzintcwmtc5mjk3ytg2otjimtbjnmu4y2nmnjg1mdiyzmq1mmeznty4owi.jpeg)
CAS RN: 105384-38-1
N,O-Bis(diethylhydrogensilyl)trifluoroacetamide [Simultaneous cyclic silylene and silyl derivatizing reagent for GC]
Product Availability
Choose a grade to view its available package options.
1 package records1 with current stock1 grade group
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20250821 | 200mg | In stock | Shandong | Inquiry |
- Product code: ICTB1435
- Purity/Analytical Methods: >85.0%(GC)
105384-38-1 / N,O-Bis(diethylhydrogensilyl)trifluoroacetamide [Simultaneous cyclic silylene and silyl derivatizing reagent for GC]
C10H22F3NOSi2 | MFCD00144992 | (E)-(DIETHYLSILYL N-(DIETHYLSILYL)-2,2,2-TRIFLUOROETHANIMIDATE)
Basic Information
CAS
105384-38-1
Multi CAS
Yes
Molecular Formula
C10H20F3NOSi2
Molecular Weight
283.440000
Exact Mass
283.103552
SMILES
CC[Si](CC)N=C(C(F)(F)F)O[Si](CC)CC
InChI
InChI=1S/C10H20F3NOSi2/c1-5-16(6-2)14-9(10(11,12)13)15-17(7-3)8-4/h5-8H2,1-4H3
InChIKey
AERQTNAPNFAWTR-UHFFFAOYSA-N
Synonyms
C10H22F3NOSi2
MFCD00144992
(E)-(DIETHYLSILYL N-(DIETHYLSILYL)-2,2,2-TRIFLUOROETHANIMIDATE)
T70048
Diethylsilyl N-(diethylsilyl)trifluoroacetimidate
Computed Properties
Structural Parameters
Heavy atom count
17
Fraction Csp3
0.9
Rotatable bonds
6
H-bond acceptors
2
Molar refractivity
68.01
TPSA
21.59
LogP / Solubility
WLOGP
4.03
MLOGP
3.55
XLogP3
4.03
Consensus LogP
3.87
Log S (ESOL)
-3.74
Class (ESOL)
Poorly soluble
Log S (Ali)
-4.79
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-5.56
Class (SILICOS-IT)
Slightly soluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-1.59
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
1.5
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