[email protected]
CAS 1050477-31-0 Finerenone molecular structure lightbox
CAS RN: 1050477-31-0

Finerenone

Product Availability

Choose a grade to view its available package options.

9 package records9 with current stock1 grade group
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20250329 100mg In stock Shanghai Inquiry
Batchno.20250406 10mg In stock Shanghai Inquiry
Batchno.20251116 1g In stock Shanghai, Tianjin Inquiry
Batchno.20250707 1mg In stock Shanghai Inquiry
Batchno.20260228 250mg In stock Shanghai Inquiry
Batchno.20260101 25mg In stock Shanghai Inquiry
Batchno.20250301 50mg In stock Shanghai, Shenzhen Inquiry
Batchno.20260226 5g In stock Shanghai Inquiry
Batchno.20250117 5mg In stock Shanghai Inquiry
  • Product code: starshine_CAS1050477-31-0
  • Purity/Analytical Methods: >99.0%
GET A QUOTE

1050477-31-0 / (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide

4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide | DTXSID201035670 | RefChem:514119

Standard CAS: 1050477-31-0 Multi CAS: Yes
Basic Information Computed Properties Safety & Transport

Basic Information

CAS
1050477-31-0
Multi CAS
Yes
Molecular Formula
C21H22N4O3
Molecular Weight
378.400000
Exact Mass
378.169191
SMILES
CCOC1=NC=C(C2=C1[C@@H](C(=C(N2)C)C(=O)N)C3=C(C=C(C=C3)C#N)OC)C
InChI
InChI=1S/C21H22N4O3/c1-5-28-21-18-17(14-7-6-13(9-22)8-15(14)27-4)16(20(23)26)12(3)25-19(18)11(2)10-24-21/h6-8,10,17,25H,5H2,1-4H3,(H2,23,26)/t17-/m1/s1
InChIKey
BTBHLEZXCOBLCY-QGZVFWFLSA-N
Synonyms
4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide DTXSID201035670 RefChem:514119 DTXCID30912349 810-201-2

Computed Properties

Structural Parameters

Heavy atom count
28
Aromatic heavy atom count
12
Fraction Csp3
0.29
Rotatable bonds
5
H-bond acceptors
6
H-bond donors
2
Molar refractivity
105.21
TPSA
110.26

LogP / Solubility

WLOGP
2.99
MLOGP
2.65
XLogP3
2.4
Consensus LogP
2.68
Log S (ESOL)
-4.05
Class (ESOL)
Slightly soluble
Log S (Ali)
-4.82
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-5.2
Class (SILICOS-IT)
Slightly soluble

ADME

GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-2.91

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
3

Safety & Transport

Pictogram(s)
Acute Toxic Health Hazard Environmental Hazard
Signal
Danger
GHS Hazard Statements
H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral] H360 (66.7%): May damage fertility or the unborn child [Danger Reproductive toxicity] H360FD (33.3%): May damage fertility; May damage the unborn child [Danger Reproductive toxicity] H362 (33.3%): May cause harm to breast-fed children [Reproductive toxicity, effects on or via lactation] H373 (33.3%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]
Precautionary Statement Codes
P203, P260, P263, P264, P270, P273, P280, P301+P316, P318, P319, P321, P330, P391, P405, and P501

Customers Also Viewed

Get In Touch

Contact Us