CAS RN: 1044871-04-6
RVX297
Product Availability
Choose a grade to view its available package options.
6 package records5 with current stock1 grade group
| Batch No. | Package | Availability | Warehouse | Inquiry |
|---|---|---|---|---|
| Batchno.20251216 | 100mg | In stock | Shanghai | Inquiry |
| Batchno.20250514 | 10mg | In stock | Shanghai | Inquiry |
| Batchno.20260628 | 1g | In stock | Shanghai | Inquiry |
| Batchno.20251225 | 250mg | Out of stock | Inquiry | |
| Batchno.20250405 | 25mg | In stock | Shanghai | Inquiry |
| Batchno.20250101 | 50mg | In stock | Shanghai | Inquiry |
- Product code: starshine_CAS1044871-04-6
- Purity/Analytical Methods: >99.0%
1044871-04-6 / 2-[3,5-dimethyl-4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,7-dimethoxy-3H-quinazolin-4-one
RVX-297 | 2-(3,5-dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3h)-one | CHEMBL4466553
Basic Information
CAS
1044871-04-6
Multi CAS
Yes
Molecular Formula
C24H29N3O4
Molecular Weight
423.500000
Exact Mass
423.215806
SMILES
CC1=CC(=CC(=C1OCCN2CCCC2)C)C3=NC4=C(C(=CC(=C4)OC)OC)C(=O)N3
InChI
InChI=1S/C24H29N3O4/c1-15-11-17(12-16(2)22(15)31-10-9-27-7-5-6-8-27)23-25-19-13-18(29-3)14-20(30-4)21(19)24(28)26-23/h11-14H,5-10H2,1-4H3,(H,25,26,28)
InChIKey
PQZDYFRDRHRZGF-UHFFFAOYSA-N
Synonyms
RVX-297
2-(3,5-dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3h)-one
CHEMBL4466553
2-{3,5-Dimethyl-4-[2-(Pyrrolidin-1-Yl)ethoxy]phenyl}-5,7-Dimethoxyquinazolin-4(3h)-One
5GD
Computed Properties
Structural Parameters
Heavy atom count
31
Aromatic heavy atom count
16
Fraction Csp3
0.42
Rotatable bonds
7
H-bond acceptors
6
H-bond donors
1
Molar refractivity
121.55
TPSA
76.68
LogP / Solubility
WLOGP
3.7
MLOGP
3.28
XLogP3
3.5
Consensus LogP
3.49
Log S (ESOL)
-4.72
Class (ESOL)
Slightly soluble
Log S (Ali)
-5.7
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-6.32
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
High
BBB permeant
Yes
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-2.68
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
3
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