CAS RN: 1038915-73-9
MK-4827 (tosylate)
Product Availability
Choose a grade to view its available package options.
9 package records8 with current stock2 grade groups
| Batch No. | Package | Availability | Warehouse | Lead Time | Inquiry |
|---|---|---|---|---|---|
| Batchno.20260422 | 100mg | In stock | Shanghai | Inquiry | |
| Batchno.20250125 | 1g | In stock | Shanghai, Shenzhen | Inquiry | |
| Batchno.20250302 | 1mg | In stock | Shanghai | Inquiry | |
| Batchno.20251122 | 250mg | In stock | Shanghai | Inquiry | |
| Batchno.20250328 | 2mg | In stock | Shanghai | Inquiry | |
| Batchno.20251130 | 50mg | In stock | Shanghai | Inquiry | |
| Batchno.20260216 | 5g | In stock | Shanghai | Inquiry | |
| Batchno.20260126 | 5mg | In stock | Shanghai | Inquiry |
| Batch No. | Package | Availability | Warehouse | Lead Time | Inquiry |
|---|---|---|---|---|---|
| Batchno.20250722 | 5mg / 25mg / 100mg | Out of stock | 5-7 business days | Inquiry |
- Product code: starshine_CAS1038915-73-9
- Purity/Analytical Methods: >99.0%
1038915-73-9 / 4-methylbenzenesulfonic acid;2-[4-[(3S)-piperidin-3-yl]phenyl]indazole-7-carboxamide
Niraparib tosylate | MK-4827 tosylate | MK-4827-tosylate
Basic Information
CAS
1038915-73-9
Multi CAS
Yes
Molecular Formula
C26H28N4O4S
Molecular Weight
492.600000
Exact Mass
492.183127
SMILES
CC1=CC=C(C=C1)S(=O)(=O)O.C1C[C@H](CNC1)C2=CC=C(C=C2)N3C=C4C=CC=C(C4=N3)C(=O)N
InChI
InChI=1S/C19H20N4O.C7H8O3S/c20-19(24)17-5-1-3-15-12-23(22-18(15)17)16-8-6-13(7-9-16)14-4-2-10-21-11-14;1-6-2-4-7(5-3-6)11(8,9)10/h1,3,5-9,12,14,21H,2,4,10-11H2,(H2,20,24);2-5H,1H3,(H,8,9,10)/t14-;/m1./s1
InChIKey
LCPFHXWLJMNKNC-PFEQFJNWSA-N
Synonyms
Niraparib tosylate
MK-4827 tosylate
MK-4827-tosylate
75KE12AY9U
DTXSID801026487
Computed Properties
Structural Parameters
Heavy atom count
35
Aromatic heavy atom count
21
Fraction Csp3
0.23
Rotatable bonds
4
H-bond acceptors
6
H-bond donors
3
Molar refractivity
135.43
TPSA
127.31
LogP / Solubility
WLOGP
3.83
MLOGP
3.41
XLogP3
3.83
Consensus LogP
3.69
Log S (ESOL)
-5.49
Class (ESOL)
Slightly soluble
Log S (Ali)
-6.37
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-6.52
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
Yes
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-3
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
4
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