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CAS 1032568-63-0 BAY 80-6946 (Copanlisib) molecular structure lightbox
CAS RN: 1032568-63-0

BAY 80-6946 (Copanlisib)

Product Availability

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8 package records8 with current stock2 grade groups
Batch No.PackageAvailabilityWarehouseLead TimeInquiry
Batchno.20260215 1mg / 5mg / 25mg / 100mg / 250mg / 1g Confirm by inquiry Shanghai, Hebei 5-7 business days Inquiry
Batch No.PackageAvailabilityWarehouseLead TimeInquiry
Batchno.20250901 100mg In stock Inquiry
Batchno.20250514 10mg In stock Inquiry
Batchno.20260225 1mg In stock Inquiry
Batchno.20250628 250mg In stock Inquiry
Batchno.20250515 25mg In stock Inquiry
Batchno.20250618 50mg In stock Inquiry
Batchno.20251216 5mg In stock Inquiry
  • Product code: SSC-004685
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Historical Factory Record

Historical Supply Reference

This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.

  • Pack sizes on record: 0.25g
  • Available purity: ≥95%
  • Inventory rows with stock: 0
  • Bulk packaging: confirmed by inquiry
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Reference Pack Sizes

Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 1032568-63-0
Pack Size Recorded Purity Available Qty Ship From Inquiry
0.25g ≥95% 0 Out of Stock Shenzhen Inquiry

1032568-63-0 / 2-amino-N-[7-methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydro-1H-imidazo[1,2-c]quinazolin-5-ylidene]pyrimidine-5-carboxamide

Copanlisib | BAY 80-6946 | BAY-80-6946

Standard CAS: 1032568-63-0 Multi CAS: Yes
Basic Information Computed Properties

Basic Information

CAS
1032568-63-0
Multi CAS
Yes
Molecular Formula
C23H28N8O4
Molecular Weight
480.500000
Exact Mass
480.223351
SMILES
COC1=C(C=CC2=C3NCCN3C(=NC(=O)C4=CN=C(N=C4)N)N=C21)OCCCN5CCOCC5
InChI
InChI=1S/C23H28N8O4/c1-33-19-17(35-10-2-6-30-8-11-34-12-9-30)4-3-16-18(19)28-23(31-7-5-25-20(16)31)29-21(32)15-13-26-22(24)27-14-15/h3-4,13-14,25H,2,5-12H2,1H3,(H2,24,26,27)
InChIKey
MWYDSXOGIBMAET-UHFFFAOYSA-N
Synonyms
Copanlisib BAY 80-6946 BAY-80-6946 BAY80-6946 BAY 80-6946 (Copanlisib)

Computed Properties

Structural Parameters

Heavy atom count
35
Aromatic heavy atom count
16
Fraction Csp3
0.43
Rotatable bonds
7
H-bond acceptors
11
H-bond donors
2
Molar refractivity
128.48
TPSA
142.01

LogP / Solubility

WLOGP
0.68
MLOGP
0.64
XLogP3
0.3
Consensus LogP
0.54
Log S (ESOL)
-3.13
Class (ESOL)
Poorly soluble
Log S (Ali)
-3.99
Class (Ali)
Poorly soluble
Log S (SILICOS-IT)
-4.19
Class (SILICOS-IT)
Slightly soluble

ADME

GI absorption
Low
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-5.17

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
No
Egan
No
Muegge
No
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
3.5

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