CAS RN: 1029939-86-3
Ralimetinib
Product Availability
Choose a grade to view its available package options.
1 package records0 with current stock1 grade group
| Batch No. | Package | Availability | Lead Time | Inquiry |
|---|---|---|---|---|
| Batchno.20251003 | 5mg | Out of stock | 5-7 business days | Inquiry |
- Product code: starshine_CAS1029939-86-3
- Purity/Analytical Methods: >99.0%
1029939-86-3 / Ralimetinib
OZ-439 | OZ 439 | RefChem:928416
Basic Information
CAS
1029939-86-3
Multi CAS
No
Molecular Formula
C28H39NO5
Molecular Weight
469.600000
Exact Mass
469.282823
SMILES
C1CC2(CCC1C3=CC=C(C=C3)OCCN4CCOCC4)OC5(C6CC7CC(C6)CC5C7)OO2
InChI
InChI=1S/C28H39NO5/c1-3-26(31-14-11-29-9-12-30-13-10-29)4-2-22(1)23-5-7-27(8-6-23)32-28(34-33-27)24-16-20-15-21(18-24)19-25(28)17-20/h1-4,20-21,23-25H,5-19H2
InChIKey
XLCNVWUKICLURR-UHFFFAOYSA-N
Synonyms
OZ-439
OZ 439
RefChem:928416
Artefenomel
Artefenomel [INN]
Computed Properties
Structural Parameters
Heavy atom count
34
Aromatic heavy atom count
6
Fraction Csp3
0.79
Rotatable bonds
5
H-bond acceptors
6
Molar refractivity
126.17
TPSA
49.39
LogP / Solubility
WLOGP
4.88
MLOGP
4.33
XLogP3
4.6
Consensus LogP
4.6
Log S (ESOL)
-5.63
Class (ESOL)
Slightly soluble
Log S (Ali)
-6.94
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-7.36
Class (SILICOS-IT)
Insoluble
ADME
GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-2.12
Drug-likeness / Medicinal Chemistry
Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
No
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
10
Customers Also Viewed
-
ethyl 5-(aminomethyl)-2-furoate hydrochloride
- CAS RN: 1030012-30-6
- Product Code: SSC-004429
-
9-[(4-chlorophenyl)thio]-6-fluoro-2,3-dihydro-1H-Pyrrolo[1,2-a]indole-1-acetic acid
- CAS RN: 1030017-51-6
- Product Code: starshine_CAS1030017-51-6
- Purity/Analytical method: >99.0%
-
IMidazo[1,2-a]pyriMidine-7-carboxylic acid, 5-Methyl-
- CAS RN: 1030017-70-9
- Product Code: starshine_CAS1030017-70-9
- Purity/Analytical method: >99.0%
-
CMP5
- CAS RN: 1030021-40-9
- Product Code: starshine_CAS1030021-40-9
- Purity/Analytical method: >99.0%
-
AEM1
- CAS RN: 1030123-90-0
- Product Code: starshine_CAS1030123-90-0
- Purity/Analytical method: >99.0%
-
2-[[1-(3-Chlorophenyl)-4-oxo-5H-pyrazolo[5,4-d]pyrimidin-6-yl]sulfanyl]propanamide
- CAS RN: 1030203-81-6
- Product Code: starshine_CAS1030203-81-6
- Purity/Analytical method: >99.0%
![CAS 1030017-51-6 9-[(4-chlorophenyl)thio]-6-fluoro-2,3-dihydro-1H-Pyrrolo[1,2-a]indole-1-acetic acid molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1030017-51-6.gif)
![CAS 1030017-70-9 IMidazo[1,2-a]pyriMidine-7-carboxylic acid, 5-Methyl- molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1030017-70-9.gif)
![CAS 1030203-81-6 2-[[1-(3-Chlorophenyl)-4-oxo-5H-pyrazolo[5,4-d]pyrimidin-6-yl]sulfanyl]propanamide molecular structure](https://starshinechemical.com/wp-content/uploads/2023/05/1030203-81-6.gif)