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CAS 1025687-58-4 R788(Fostamatinib disodium) molecular structure lightbox
CAS RN: 1025687-58-4

R788(Fostamatinib disodium)

Product Availability

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8 package records6 with current stock2 grade groups
Batch No.PackageAvailabilityWarehouseLead TimeInquiry
Batchno.20250223 100mg In stock Shanghai Inquiry
Batchno.20250309 10mg In stock Shanghai, Tianjin Inquiry
Batchno.20251003 1g Out of stock Inquiry
Batchno.20260629 1mg In stock Shanghai Inquiry
Batchno.20260502 250mg In stock Shanghai Inquiry
Batchno.20260422 50mg In stock Shanghai Inquiry
Batchno.20250120 5mg In stock Shanghai Inquiry
Batch No.PackageAvailabilityWarehouseLead TimeInquiry
Batchno.20250214 10mg / 50mg / 250mg Out of stock 5-7 business days Inquiry
  • Product code: SSC-003818
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Historical Factory Record

Historical Supply Reference

This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.

  • Pack sizes on record: 0.25g
  • Available purity: ＞97%
  • Inventory rows with stock: 0
  • Bulk packaging: confirmed by inquiry
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Reference Pack Sizes

Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 1025687-58-4
Pack Size Recorded Purity Available Qty Ship From Inquiry
0.25g ＞97% 0 Out of Stock Hong Kong Inquiry

1025687-58-4 / disodium;[6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)pyrimidin-4-yl]amino]-2,2-dimethyl-3-oxopyrido[3,2-b][1,4]oxazin-4-yl]methyl phosphate;hexahydrate

R788 disodium | R788(Fostamatinib disodium) | R 788 sodium

Standard CAS: 1025687-58-4 Multi CAS: Yes
Basic Information Computed Properties Safety & Transport

Basic Information

CAS
1025687-58-4
Multi CAS
Yes
Molecular Formula
C23H36FN6Na2O15P
Molecular Weight
732.500000
Exact Mass
732.175568
SMILES
CC1(C(=O)N(C2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)COP(=O)([O-])[O-])C.O.O.O.O.O.O.[Na+].[Na+]
InChI
InChI=1S/C23H26FN6O9P.2Na.6H2O/c1-23(2)21(31)30(11-38-40(32,33)34)20-14(39-23)6-7-17(28-20)27-19-13(24)10-25-22(29-19)26-12-8-15(35-3)18(37-5)16(9-12)36-4;;;;;;;;/h6-10H,11H2,1-5H3,(H2,32,33,34)(H2,25,26,27,28,29);;;6*1H2/q;2*+1;;;;;;/p-2
InChIKey
ZQGJCHHKJNSPMS-UHFFFAOYSA-L
Synonyms
R788 disodium R788(Fostamatinib disodium) R 788 sodium Fostamatinib disodium anhydrous R788 (Fostamatinib) Disodium

Computed Properties

Structural Parameters

Heavy atom count
48
Aromatic heavy atom count
18
Fraction Csp3
0.3
Rotatable bonds
10
H-bond acceptors
14
H-bond donors
2
Molar refractivity
156.32
TPSA
381.38

LogP / Solubility

WLOGP
-9.11
MLOGP
-7.95
XLogP3
-9.11
Consensus LogP
-8.72
Log S (ESOL)
1.74
Class (ESOL)
Highly soluble
Log S (Ali)
1.01
Class (Ali)
Highly soluble
Log S (SILICOS-IT)
1.94
Class (SILICOS-IT)
Highly soluble

ADME

GI absorption
Low
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
No
CYP2C9 inhibitor
No
CYP2D6 inhibitor
No
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-13.66

Drug-likeness / Medicinal Chemistry

Lipinski
No
Ghose
No
Veber
No
Egan
No
Muegge
No
Bioavailability score
0.17
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
4.5

Safety & Transport

Pictogram(s)
Acute Toxic Health Hazard
Signal
Danger
GHS Hazard Statements
H301 (75%): Toxic if swallowed [Danger Acute toxicity, oral] H361 (100%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]
Precautionary Statement Codes
P203, P264, P270, P280, P301+P316, P318, P321, P330, P405, and P501

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