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CAS 1018674-83-3 N-[2-[6-[[(3,4-Dichlorophenyl)Methyl]aMino]-2-(4-Methoxyphenyl)-3-oxopyrido[2,3-b]pyrazin-4(3H)-yl]ethyl]-acetaMide molecular structure lightbox
CAS RN: 1018674-83-3

N-[2-[6-[[(3,4-Dichlorophenyl)Methyl]aMino]-2-(4-Methoxyphenyl)-3-oxopyrido[2,3-b]pyrazin-4(3H)-yl]ethyl]-acetaMide

Product Availability

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5 package records5 with current stock1 grade group
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20260408 100mg In stock Shanghai Inquiry
Batchno.20251107 10mg In stock Shanghai Inquiry
Batchno.20260117 250mg In stock Shanghai Inquiry
Batchno.20250605 25mg In stock Shanghai Inquiry
Batchno.20250414 50mg In stock Shanghai Inquiry
  • Product code: SSC-002918
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Historical Factory Record

Historical Supply Reference

This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.

  • Pack sizes on record: 0.25g
  • Available purity: ≥95%
  • Inventory rows with stock: 0
  • Bulk packaging: confirmed by inquiry
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Reference Pack Sizes

Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 1018674-83-3
Pack Size Recorded Purity Available Qty Ship From Inquiry
0.25g ≥95% 0 Out of Stock Hong Kong Inquiry

1018674-83-3 / N-[2-[6-[(3,4-dichlorophenyl)methylamino]-2-(4-methoxyphenyl)-3-oxopyrido[2,3-b]pyrazin-4-yl]ethyl]acetamide

cvt-11127 | N-(2-(6-((3,4-Dichlorobenzyl)amino)-2-(4-methoxyphenyl)-3-oxopyrido[2,3-b]pyrazin-4(3H)-yl)ethyl)acetamide | N-[2-[6-[[(3,4-Dichlorophenyl)methyl]amino]-2-(4-methoxyphenyl)-3-oxopyrido[2,3-b]pyrazin-4(3H)-yl]ethyl]-acetamide

Standard CAS: 1018674-83-3 Multi CAS: Yes
Basic Information Computed Properties

Basic Information

CAS
1018674-83-3
Multi CAS
Yes
Molecular Formula
C25H23Cl2N5O3
Molecular Weight
512.400000
Exact Mass
511.117795
SMILES
CC(=O)NCCN1C2=C(C=CC(=N2)NCC3=CC(=C(C=C3)Cl)Cl)N=C(C1=O)C4=CC=C(C=C4)OC
InChI
InChI=1S/C25H23Cl2N5O3/c1-15(33)28-11-12-32-24-21(30-23(25(32)34)17-4-6-18(35-2)7-5-17)9-10-22(31-24)29-14-16-3-8-19(26)20(27)13-16/h3-10,13H,11-12,14H2,1-2H3,(H,28,33)(H,29,31)
InChIKey
PVTIQVJHZDSETN-UHFFFAOYSA-N
Synonyms
cvt-11127 N-(2-(6-((3,4-Dichlorobenzyl)amino)-2-(4-methoxyphenyl)-3-oxopyrido[2,3-b]pyrazin-4(3H)-yl)ethyl)acetamide N-[2-[6-[[(3,4-Dichlorophenyl)methyl]amino]-2-(4-methoxyphenyl)-3-oxopyrido[2,3-b]pyrazin-4(3H)-yl]ethyl]-acetamide CHEMBL495191 N-(2-(6-(3,4-dichlorobenzylamino)-2-(4-methoxyphenyl)-3-oxopyrido[2,3-b]pyrazin-4(3H)-yl)ethyl)acetamide

Computed Properties

Structural Parameters

Heavy atom count
35
Aromatic heavy atom count
22
Fraction Csp3
0.2
Rotatable bonds
8
H-bond acceptors
7
H-bond donors
2
Molar refractivity
138.26
TPSA
98.14

LogP / Solubility

WLOGP
4.52
MLOGP
4.02
XLogP3
4.2
Consensus LogP
4.25
Log S (ESOL)
-5.8
Class (ESOL)
Slightly soluble
Log S (Ali)
-7.03
Class (Ali)
Insoluble
Log S (SILICOS-IT)
-7.7
Class (SILICOS-IT)
Insoluble

ADME

GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
No
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
No
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
Yes
Log Kp (skin permeation)
-2.63

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
No
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Leadlikeness
No
Synthetic Accessibility
3

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