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CAS 1009820-21-6 CX-4945 molecular structure lightbox
CAS RN: 1009820-21-6

CX-4945

Product Availability

Choose a grade to view its available package options.

10 package records9 with current stock2 grade groups
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20260130 100mg In stock Shanghai, Tianjin Inquiry
Batchno.20260115 1g In stock Shanghai Inquiry
Batchno.20250804 1mg In stock Shanghai Inquiry
Batchno.20250111 250mg In stock Shanghai Inquiry
Batchno.20250403 50mg In stock Shanghai Inquiry
Batchno.20251114 5g In stock Shanghai Inquiry
Batchno.20260307 5mg In stock Shanghai Inquiry
Batch No.PackageAvailabilityWarehouseInquiry
Batchno.20250802 10mg In stock Inquiry
Batchno.20251220 50mg Out of stock Inquiry
Batchno.20260424 5mg In stock Inquiry
  • Product code: SSC-001779
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Historical Factory Record

Historical Supply Reference

This product has historical factory records. Recorded pack sizes and purity can be used as a supply reference, while project-specific availability is confirmed by inquiry.

  • Pack sizes on record: 1g
  • Available purity: ＞97%
  • Inventory rows with stock: 0
  • Bulk packaging: confirmed by inquiry
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Reference Pack Sizes

Reference pack sizes are shown below. Final availability, packaging and delivery schedule are confirmed by inquiry.

Recorded sizes, purity and stock details for CAS 1009820-21-6
Pack Size Recorded Purity Available Qty Ship From Inquiry
1g ＞97% 0 Out of Stock Shanghai Inquiry

1009820-21-6 / 5-(3-chloroanilino)benzo[c][2,6]naphthyridine-8-carboxylic acid

Silmitasertib | CX-4945 | CX 4945

Standard CAS: 1009820-21-6 Multi CAS: No
Basic Information Computed Properties

Basic Information

CAS
1009820-21-6
Multi CAS
No
Molecular Formula
C19H12ClN3O2
Molecular Weight
349.800000
Exact Mass
349.061804
SMILES
C1=CC(=CC(=C1)Cl)NC2=NC3=C(C=CC(=C3)C(=O)O)C4=C2C=CN=C4
InChI
InChI=1S/C19H12ClN3O2/c20-12-2-1-3-13(9-12)22-18-15-6-7-21-10-16(15)14-5-4-11(19(24)25)8-17(14)23-18/h1-10H,(H,22,23)(H,24,25)
InChIKey
MUOKSQABCJCOPU-UHFFFAOYSA-N
Synonyms
Silmitasertib CX-4945 CX 4945 CX4945 Cx-4945 free acid

Computed Properties

Structural Parameters

Heavy atom count
25
Aromatic heavy atom count
20
Rotatable bonds
3
H-bond acceptors
4
H-bond donors
2
Molar refractivity
98.74
TPSA
75.11

LogP / Solubility

WLOGP
4.88
MLOGP
4.31
XLogP3
4.4
Consensus LogP
4.53
Log S (ESOL)
-5.48
Class (ESOL)
Slightly soluble
Log S (Ali)
-5.95
Class (Ali)
Slightly soluble
Log S (SILICOS-IT)
-6.34
Class (SILICOS-IT)
Insoluble

ADME

GI absorption
High
BBB permeant
No
P-gp substrate
No
CYP1A2 inhibitor
Yes
CYP2C19 inhibitor
Yes
CYP2C9 inhibitor
Yes
CYP2D6 inhibitor
Yes
CYP3A4 inhibitor
No
Log Kp (skin permeation)
-1.39

Drug-likeness / Medicinal Chemistry

Lipinski
Yes
Ghose
Yes
Veber
Yes
Egan
Yes
Muegge
Yes
Bioavailability score
0.55
Brenk alerts
1
Leadlikeness
No
Synthetic Accessibility
3

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